Results 31 to 40 of about 108,865 (249)

Mitochondrial Transplantation via Magnetically Responsive Artificial Cells Promotes Intracerebral Hemorrhage Recovery by Supporting Microglia Immunological Homeostasis

Advanced Materials, Volume 37, Issue 13, April 2, 2025.
A type of magnetically responsive artificial cells (ACs) has been developed, demonstrating the loading of mitochondria and self‐enclosure processes to ensure the protection of mitochondrial transport via the bloodstream. The treatment with ACs effectively transplanted mitochondria around the lesion, thereby improving neurological recovery by supporting
Mi Zhou, Jinhui Zang, Yuxuan Qian, Qiang Zhang, Yifan Wang, Tingting Yao, Hongyu Yan, Kai Zhang, Xiaojun Cai, Lixian Jiang, Yuanyi Zheng   +10 more
wiley   +1 more source

Deoxyribonucleic Acid Extraction Using Iron Oxide Nanoparticle-based Method in Forensic Investigations

Journal of Forensic Science and Medicine
Extraction of deoxyribonucleic acid (DNA) plays a pivotal role in molecular biology, cell biology, genetic research, and forensic inquiries. In the realm of forensic science, the selection of an efficient DNA extraction method holds utmost importance, as
Imran Khan, Gaurav Kaushik
doaj   +1 more source

A Cross-Sectional Study Investigating the Relationship Between Alexithymia and Suicide, Violence, and Dual Harm in Male Prisoners

Frontiers in Psychiatry, 2021
Background: Suicide and violence are common within male prisoners. One suggested risk factor for both behaviors is alexithymia. Alexithymia describes a deficit in identifying and describing feelings and is also related to externally oriented thinking ...
Laura Hemming, Laura Hemming, Jennifer Shaw, Jennifer Shaw, Jennifer Shaw, Gillian Haddock, Gillian Haddock, Gillian Haddock, Lesley-Anne Carter, Lesley-Anne Carter, Daniel Pratt, Daniel Pratt, Daniel Pratt   +12 more
doaj   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

Co‐production and adaptation of a prison‐based problem‐solving workbook to support the mental health of patients housed within a medium‐ and low‐secure forensic service

Health Expectations
Introduction Problem‐solving skills (PSS) help to provide a systematic approach to dealing with and managing complex problems. The overall aim of this study was to assess the acceptability and feasibility of developing and adapting a prison‐based PSS ...
Amanda E. Perry, Heather Baker, Anne Aboaja, Lindsey Wilson, Sarah Morris, Patient Public Involved Service User   +5 more
doaj   +1 more source

Effectiveness and mechanisms of the arts therapies in forensic care. A systematic review, narrative synthesis, and meta analysis

Frontiers in Psychiatry, 2023
IntroductionMental health care provided to offenders with psychiatric problems in forensic settings mainly consists of verbal oriented treatments. In addition, experience-based therapies are used such as (creative) arts therapies: (visual) art therapy ...
Annemarie Abbing, Annemarie Abbing, Annemarie Abbing, Suzanne Haeyen, Suzanne Haeyen, Suzanne Haeyen, Sashank Nyapati, Peter Verboon, Susan van Hooren   +8 more
doaj   +1 more source

High‐Fidelity Synthetic Data Replicates Clinical Prediction Performance in a Million‐Patient Diabetes Cohort

Advanced Science, EarlyView.
This study generates high‐fidelity synthetic longitudinal records for a million‐patient diabetes cohort, successfully replicating clinical predictive performance. However, deeper analysis reveals algorithmic biases and trajectory inconsistencies that escape standard quality metrics. These findings challenge current validation norms, demonstrating why a
Francisco Ortuño, Víctor M. de la Oliva Roque, Javier‐Ignacio Ramirez‐Lopez, David P. Kreil, Joaquín Dopazo, Carlos Loucera   +5 more
wiley   +1 more source

Molecular techniques for identifying intraguild predators of fishers and other North American small carnivores

Wildlife Society Bulletin, 2013
Identifying predators of threatened and endangered species is important for understanding and reducing the impacts of predation. Visible evidence collected from a carcass alone is often insufficient to accurately identify predator species.
Greta M. Wengert, Mourad W. Gabriel, Janet E. Foley, Teri Kun, Benjamin N. Sacks   +4 more
doaj   +1 more source

Sexual knowledge of Queensland forensic mental health patients: A cross-sectional quantitative study

Frontiers in Psychiatry, 2023
Forensic patients with serious mental illnesses (SMI) encounter significant challenges including active symptomatology, associated social and interpersonal impairments, psychotropic medication side effects and institutionalization, all of which ...
Elnike Brand, Ching Tham, Angela Ratsch, Angela Ratsch, Edward Heffernan   +4 more
doaj   +1 more source

ACSL1‐Dependent Microglial Lipoimmunometabolic Reprogramming Underlies Cognitive Deficits in Alcohol Use Disorder

Advanced Science, EarlyView.
This study reveals that chronic alcohol exposure selectively upregulates ACSL1 expression in prefrontal cortical microglia, driving lipid metabolism reprogramming and lipid droplet accumulation, which activates the NLRP3 inflammasome and sustains neuroinflammation. To reverse this process, a dual‐targeted lipid nanoparticle, siACSL1@LNP‐MR, is designed
Liang Hao, Xing‐Rui Cao, Bai‐Qiang Li, Fu‐Ying Zhao, Jia‐Mei Wang, Rui‐Kang Gao, Zhi‐Peng Cao, Zhen‐Xian Du, Hua‐Qin Wang   +8 more
wiley   +1 more source