Results 41 to 50 of about 198,556 (263)
Selective Modulation of OTUB1 Noncanonical Function via a bioPhosTAC Strategy
Advanced Science, EarlyView.This work positions the versatile performance of the peptide‐based bioPhosTAC platform for dissecting phosphorylation‐dependent biology and expanding the scope of induced‐proximity technologies. We demonstrated that selective manipulation of a tyrosine phosphorylation site is sufficient to propagate coordinated cellular consequences.
Seung Un Seo +7 more
wiley +1 more source
Advanced Science, EarlyView.Macrophage RSAD2 dually regulates CMPK2—the rate‐limiting enzyme for mitochondrial DNA synthesis—by suppressing its ubiquitination and promoting its phosphorylation via Csnk2a2 recruitment. This amplifies mtDNA production, which simultaneously activates a cGAS‐STING‐IRF3‐RSAD2 feedforward loop and the NLRP3 inflammasome, driving a self‐sustaining ...
Haomiao Yuan +16 more
wiley +1 more source
Palaeoproteomic Deconvolution of Physical and Genetic Collagen Mixtures
Advanced Science, EarlyView.ClassiCOL_v2 uses a novel “peptide patching” framework that treats any collagen sample as a patchwork of peptide sequences derived from phylogenetically related species. This allows the algorithm to simultaneously resolve two previously intractable problems: multi‐species samples and/or database deficiencies.
Ian Engels +12 more
wiley +1 more source
The foot in forensic human identification - a review [PDF]
, 2014 The identification of human remains is a process which can be attempted irrespective of the stage of decomposition in which the remains are found or the anatomical regions recovered. In recent years, the discovery of fragmented human remains has garnered
Hackman, L. +4 more
core +1 more source
Identification and Resolution of Capability Gaps in Forensic Science [PDF]
Although forensic biology is a powerful tool in criminal investigations, there are a number of capability gaps; namely, the interpretation of low-level DNA mixtures, associating the DNA profile with a body fluid, and the issue of consent in sexual ...
Williams, Graham Andrew
core +3 more sources
Money laundering, embezzlement and tax evasion: a teaching case
Revista Ambiente ContábilPurpose: This teaching case aims to deepen the knowledge related to money laundering, misappropriation and tax evasion, to encourage the debate in classroom on the accountant's responsibility and ethical dilemma when faced with evidence that their ...
Rodrigo de Souza Gonçalves +2 more
doaj +1 more source
American Journal of Community Psychology, EarlyView.Abstract This article examines the psychological effects of migration detention in the European Union's Closed Controlled Access Center (CCAC) on Samos through an ecological lens. It explores a double normalization of suffering: the brutalization of necropolitical migration governance and the simultaneous understanding of resulting distress as an ...
Julia Manek
wiley +1 more source
The philosophy, nature and practice of forensic sediment analysis [PDF]
, 2007 The rapidly expanding field of forensic geoscience derives its roots from nineteenth-and early twentieth-century scientists who both influence and are influenced by literature and fictional writing.
Morgan, RM, Bull, PA
core
On Using Gait in Forensic Biometrics
, 2011 Given the continuing advances in gait biometrics, it appears prudent to investigate the translation of these techniques for forensic use. We address the question as to the confidence that might be given between any two such measurements.
Nixon, Mark +9 more
core +1 more source
Australian Journal of Social Issues, EarlyView.ABSTRACT Robust measurement of disadvantage is essential to identifying and addressing inequities in children's development. We tested how a multidimensional framework of child disadvantage performed relative to a traditional socioeconomic position (SEP) approach to predict developmental outcomes.
Wei Hong +7 more
wiley +1 more source