Results 21 to 30 of about 13,886 (258)

Data reduction and data mining framework for digital forensic evidence: storage, intelligence, review and archive [PDF]

, 2014
With the volume of digital forensic evidence rapidly increasing, this paper proposes a data reduction and data mining framework that incorporates a process of reducing data volume by focusing on a subset of information.
Kim-Kwang Raymond Choo, Darren Quick
core  

Ergonomics and Forensic Engineering

Journal of the National Academy of Forensic Engineers, 2021
In disputes, forensic engineers routinely investigate available hardware and software and may examine other engineering attributes and activities. Human factors and ergonomic (HF&E) aspects may be considered, but these tend to be more limited or overlooked.
George Samaras, EA Samaras
openaire   +2 more sources

EEPD1 Inhibition Unleashes Antitumor Immunity in Colorectal Cancer by Activating the cGAS‐STING Pathway

Advanced Science, EarlyView.
In colorectal cancer, high expression of the DNA repair protein EEPD1 correlates with immune exclusion and poor prognosis. This study demonstrates that EEPD1 depletion induces genomic instability, leading to cytosolic DNA accumulation and subsequent activation of the cGAS‐STING‐type I interferon pathway. This cascade remodels the tumor microenvironment
Liyun Huo, Chong Wu, Xiaobo Li, Caina Ma, Jiamin Huang, Zishuo Chen, Weiling He, Tianyu Tao, Weijing Zhang   +8 more
wiley   +1 more source

TME/NIR Dual‐Responsive Zinc‐Based Targeted Nanoagonist for Multimodal Amplification of STING‐Mediated Cancer Immunotherapy

Advanced Science, EarlyView.
A multifunctional nanoagonist (cDZ@IP) enables nano‐metabolite–driven multimodal activation of the STING pathway and enhanced immune recognition, achieving potent antitumor immunity and suppressing tumor growth and metastasis. This strategy highlights the rational design of therapeutic metabolites and establishes a new paradigm bridging nanomedicine ...
Kepeng Hu, Jiawei Wang, Wei Zhang, Zhixuan Wu, Jing Chen, Yujing He, Xiyue Duan, Yaoting He, Xin Xin, Haoyi Xiang, Yijing Wang, Chengwei Wu, Yang Yi, Qing Meng, Yuqian Qiao, Kui Cheng, Xiaojun Long, Zhangfa Song   +17 more
wiley   +1 more source

A comparison of forensic toolkits and mass market data recovery applications [PDF]

, 2013
Digital forensic application suites are large, expensive, complex software products, offering a range of functions to assist in the investigation of digital artifacts.
Buchanan-Wollaston, J., Storer, T., Glisson, W.   +2 more
core  

Palatable‐Food–Driven Top‐Down Circuit Inhibits PVNCRF Activity to Mitigate Stress Via Peri‐PVNCRFR1 Neurons

Advanced Science, EarlyView.
Palatable food alleviates stress and prevents anxiety. This study uncovers a dedicated neural pathway: dopamine release in the PFC activates D1R neurons, whose projections to the peri‐PVN engage a population of anxiolytic CRFR1 neurons. These neurons then inhibit stress‐induced hyperactivity of PVNCRF neurons, providing a circuit‐level explanation for ...
Yuchuan Hong, Shirui Jun, Tianjiao Deng, Gaojie Shao, Dan Liu, Yi Sun, Yan Chen, Qian Xiao, Jie Shao, Sheng Wang, Tianwen Huang, Fan Yang, Jie Tu   +12 more
wiley   +1 more source

Enhancing Biogenic Formic Acid Production in the Modified OxFA Process by Acetonitrile Addition

Advanced Science, EarlyView.
In this study, the beneficial effect of using acetonitrile as a co‐solvent in the modified OxFA process is shown, outperforming methanol, demonstrating improved reaction kinetics combined with high selectivity for the HPA‐2 (H5PV2Mo10O40) catalyzed oxidation of xylose to FA.
Jan‐Dominik H. Krueger, Pegah Saedi, Maximilian J. Poller, Alberto Collauto, Jason P. Hallett, David Robinson, Maxie M. Roessler, Jakob Albert   +7 more
wiley   +1 more source

Improving reliability in forensic engineering: the Delft approach

, 2018
Based on established theories from literature and best practices of forensic investigations in aerospace engineering, civil engineering and biomechanical engineering, the Delft University of Technology has developed a Delft approachfor forensic ...
Terwel, K.C. (author), Schuurman, M.J. (author), Terwel, K.C., Loeve, A.J. (author), Schuurman, M.J., Loeve, A.J.   +5 more
core   +1 more source

Conformational Snapshots of CydDC in a Native Lipid Bilayer Coupling Heme Transport to Antibiotic Resistance

Advanced Science, EarlyView.
Phylogenetic and biochemical analyses of the heme transporter CydDC reveal its functional conservation throughout bacterial evolution and demonstrate its unique asymmetric allosteric mechanism. Furthermore, impairment of CydDC function directly affects bacterial antibiotic resistance and likely compromises antibiotic efficacy through drug efflux.
Lili Yang, Changbin Zhang, Mengyuan Lyu, Yongbo Luo, Jierou Zhang, Yujiao Chen, Lintao Luo, Wen Qiao, Xiangyangpeng Li, Yu Zhou, Zhongling Wei, Yuling Xiao, Qian Niu, Juan Zhou, Guanglin He, Binwu Ying, Zhaoming Su, Hao Chen, Xiaodi Tang, Haohao Dong   +19 more
wiley   +1 more source

Briefing: Activities by IABSE WG8 (Forensic Structural Engineering)

, 2016
A working group on forensic engineering (WG8) was established within the International Association for Bridge and Structural Engineering (IABSE) in 2011.
Terwel, K.C. (author), Palmisano, Fabrizio, Terwel, K.C., Palmisano, Fabrizio (author)   +3 more
core   +1 more source