Results 61 to 70 of about 110,949 (340)

Multiomics Analyses Reveal an Essential Role of Tryptophan in Treatment of csDMARDs in Rheumatoid Arthritis

open access: yesAdvanced Science, EarlyView.
Rheumatoid arthritis is a disease characterized by joint inflammation. Approximately 50% of patients show insufficient response to traditional synthetic disease‐modifying antirheumatic drugs. This study aims to elucidate differential molecular profiles of the mechanisms underlying drug responses through multi‐omics strategy.
Congcong Jian   +26 more
wiley   +1 more source

The effect of mark enhancement techniques on the presumptive and confirmatory tests for blood [PDF]

open access: yes, 2018
An investigation into the effects of physical and chemical enhancement on subsequent presumptive and confirmatory tests for human blood is presented. Human blood was deposited onto porous (white 80gsm paper and brown envelope) and non-porous (tile and ...
Deacon, Paul   +4 more
core   +4 more sources

Reliable AI Platform for Monitoring BCI Caused Brain Injury and Providing Real‐Time Protection

open access: yesAdvanced Science, EarlyView.
BrainGuard enables real‐time and interpretable assessment of brain injury caused by brain computer interface (BCI). Using feature‐based Gaussian process (GP) emulators trained on limited biomechanical data, it efficiently predicts full‐field strain and constructs patient‐specific digital brain twins to support clinical diagnosis and long‐term BCI ...
Chufan He   +3 more
wiley   +1 more source

The issue of hazardous materials sampling for the forensic purposes with application of risk engineering methods [PDF]

open access: yes, 2014
The Risk Engineering and its methods are applied to many scientific disciplines. The gained knowledge and values are used in practice where they help experts for better orientation in the issue and accelerating the related processes. This article aims to
Adamec, Vladimír   +4 more
core  

LncRNA THUMPD3‐AS1 Regulates Behavioral and Synaptic Structural Abnormalities in Schizophrenia via miR‐485‐5p and ARHGAP8

open access: yesAdvanced Science, EarlyView.
Schizophrenia (SCZ) is linked to synaptic structural deficits driven by dysregulated noncoding RNAs. Using the novel ceRNAxis pipeline, THUMPD3‐AS1/miR‐485‐5p/ARHGAP8 is identified as a key regulator of actin cytoskeletal remodeling through noncanonical RhoB/C‐ROCK2 signaling. Modulating this axis ameliorates SCZ‐like phenotypes in mice and aligns with
Xiaojuan Gong   +9 more
wiley   +1 more source

A comparative study of teaching forensics at a university degree level [PDF]

open access: yes, 2006
Computer forensics is a relatively young University discipline which has developed strongly in the United States and the United Kingdom but is still in its infancy in continental Europe.
Anderson, Philip   +6 more
core   +1 more source

A Degradable Bioinspired Flier with Aerogel‐Based Colorimetric Sensors for Environmental Monitoring

open access: yesAdvanced Science, EarlyView.
Biodegradable fliers are developed inspired by Tipuana tipu samaras, integrating cellulose nanocrystal aerogel (CNCa) sensors loaded with natural dyes for pH and ammonia detection. The lightweight, degradable fliers mimic natural morphology and aerodynamics, offering an eco‐friendly, scalable solution for in situ environmental monitoring after passive ...
Gianpaolo Gallo   +4 more
wiley   +1 more source

A comparison of forensic toolkits and mass market data recovery applications [PDF]

open access: yes, 2013
Digital forensic application suites are large, expensive, complex software products, offering a range of functions to assist in the investigation of digital artifacts.
Buchanan-Wollaston, J.   +2 more
core  

Rigor Mortis and News obtained by the Body\u2019s Scientific Reconstruction of the Turin Shroud Man [PDF]

open access: yes, 2018
After various tentative to artistically build a tridimensional form of the Turin Shroud (TS) Man, the authors faced the problem of the scientific construction of a 3D model of this Man with an accuracy of the order of 1 cm.
Bevilacqua, Matteo   +4 more
core   +1 more source

Ferroptosis‐Mediated Hippocampal Neuronal Loss Post‐mTBI: Chromatin Accessibility Profiling and Single‐Nucleus Transcriptomics

open access: yesAdvanced Science, EarlyView.
Hippocampal single ‐nucleus transcriptomes and chromatin accessibility after mild traumatic brain injury reveal dentate granule neuron vulnerability driven by ferroptosis. The c‐Jun–Tmsb4x–Slc2a2 axis modulates lipid peroxidation and iron dysregulation.
Manrui Li   +13 more
wiley   +1 more source

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