Results 171 to 180 of about 16,480,188 (390)

Isomer Composition Assessment of Synthetic Phosphatidylethanol by Collision‐Induced and Ozone‐Induced Dissociation Mass Spectrometry

open access: yesDrug Testing and Analysis, EarlyView.
This study examines the isomeric composition of PEth reference materials and compares it with the natural variation in isomer distribution found in blood samples. ABSTRACT The direct blood‐alcohol biomarker phosphatidylethanol (PEth), especially its most abundant analogue 1‐palmitoyl‐2‐oleoyl‐sn‐phosphatidylethanol (PEth 16:0/18:1) has gained ...
Matthias Bantle   +6 more
wiley   +1 more source

Iontophoretic Delivery of Hyaluronic Acid Nanogel-Loaded Fermented Rice Extract Mitigates Skin Glycation

open access: yesInternational Journal of Nanomedicine
Yuanyuan Han,1,2,* Yunzhi Lin,3,* Miao Guo,4 Yinshu Wang,1,2 Xiuju Dong,1,2 Lidan Xiong,1,2 Li Li,1– 3 Hua Wang,4 Xuefeng Hu,5,6 Fan Yang4 1Evaluation Center for Cosmetics Safety and Efficacy, West China Hospital, Sichuan University ...
Han Y   +9 more
doaj  

Analytical Challenges in Detecting New Psychoactive Substances in Anti‐Doping: A Proof‐of‐Concept Involving Pentedrone Metabolite

open access: yesDrug Testing and Analysis, EarlyView.
The paper describes an investigation related to the pentedrone norephedrine metabolite. The athlete's sample was analyzed using ultra‐performance liquid chromatography–tandem mass spectrometry (UPLC–MS/MS). According to the literature, this metabolite may originate from pentedrone, α‐pyrrolidinopentiophenone (PVP), or N‐ethylpentedrone (NEP).
D. Kwiatkowska   +8 more
wiley   +1 more source

Detection of a Distinct Erythropoietin (EPO) Profile After Isoelectric Focusing in Patients With Familial Erythrocytosis

open access: yesDrug Testing and Analysis, EarlyView.
A basic EPO IEF profile was identified in patients with familial erythropoiesis linked to mutations in noncoding parts of EPO gene. Comparison of blood and urine EPO profiles from these patients differed from adult wild‐type EPO (WT) and from Eprex‐administered patients. Patients' EPO do not differ from WT EPO after analysis using SDS‐PAGE/SAR‐PAGE. It
Laurent Martin   +9 more
wiley   +1 more source

Neural Network‐Based Detection of Adulterants in Opioid Samples Using IR Absorption Spectroscopy

open access: yesDrug Testing and Analysis, EarlyView.
We construct a neural network for the classification of bromazolam and fluorofentanyl in illicit opioid samples. The model outperforms a random forest classifier and shows elevated performance for low concentration samples. ABSTRACT Community‐based drug checking services are challenged in their ability to reliably detect low concentration adulterants ...
Joshua Jai   +4 more
wiley   +1 more source

Concentration and Detection Time of Nitrous Oxide in Blood Following Controlled Inhalation

open access: yesDrug Testing and Analysis, EarlyView.
In a study with controlled inhalation of nitrous oxide (N2O), elimination followed a two‐compartment model with half‐lives of 2.4 and 31 min, and N2O remained detectable in blood samples for 1–3 h after inhalation. ABSTRACT Recreational use of nitrous oxide (laughing gas, N2O) is becoming increasingly common and abuse is often seen in relation to ...
Angelica Ørregaard Lindholm   +5 more
wiley   +1 more source

Forensic veterinary evaluation of gunshot wounds to a dog’s head based on traditional examination methods and modern imaging techniques [PDF]

open access: diamond, 2019
Kinga Panasiuk-Flak   +6 more
openalex   +1 more source

Statistical Discrimination of Urinary Steroid Biomarkers in the Athlete Biological Passport: A Novel Approach to an Abnormal Steroid Profile Score (ASPS)

open access: yesDrug Testing and Analysis, EarlyView.
The study developed a single Abnormal Steroid Profile Score (ASPS) to improve interpretation of the Athlete Biological Passport steroid module. Using Bayesian modelling and logistic regression, biomarker patterns from laboratory and doping control data successfully discriminated between doped and clean individuals, with improved classification ...
James G. Hopker   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy