Results 141 to 150 of about 1,766,646 (254)

Medical-forensic research of injuries on the skulls discovered during archaeological excavations on Bolgar fortified settlement

open access: yesПоволжская археология, 2015
The article presents some preliminary results of medical and forensic analysis of traumatic injuries on the skulls from medieval burials found on the territory of Bolgar fortified settlement.
Albert I. Zholobov   +2 more
doaj  

Antidepressant Misuse in Esports: A Review of Pharmacology, Adverse Effects, Pharmacokinetics and Biomatrix‐Based Detection for Anti‐Doping Applications

open access: yesDrug Testing and Analysis, EarlyView.
This review highlights the misuse of antidepressants as potential cognitive‐enhancing agents in Esports. Despite pharmacological effects that overlap with those of psychostimulants, antidepressants remain an under‐recognised source of doping in Esports.
Kassim Ali Salum   +4 more
wiley   +1 more source

Monitoring Injected Drug Use in Greece Through Syringe Residue Analysis: A Multicity Study Within the ESCAPE Network

open access: yesDrug Testing and Analysis, EarlyView.
A total of 2121 used syringes were analyzed in Athens, Thessaloniki, and Patras between 2022 and 2024. Distinct drug‐use patterns were observed across the three cities. Benzodiazepines, pregabalin, methadone, and fentanyl were increasingly detected in 2024.
Christina Matiaki   +10 more
wiley   +1 more source

An Investigation Into the Yields of 3,4‐Methylenedioxyphenyl‐2‐propanone (MDP2P) From Glycidate Pre‐Precursors

open access: yesDrug Testing and Analysis, EarlyView.
Hydrolysis of the glycidate pre‐precursors MMDMG and EMDMG was evaluated for MDP2P production. Acid hydrolysis of MMDMG (HCl, 100°C, 18 h) yielded the highest MDP2P recovery (79%), whereas base hydrolysis produced only slightly lower yields (73%), demonstrating both pathways are effective routes to this key MDMA precursor.
Alexandra L. Mercieca   +4 more
wiley   +1 more source

Population Pharmacokinetics and Detection Times of Betamethasone After Intravenous, Intramuscular, and Intranasal Jet Administration of Betamethasone Sodium Phosphate in Horses

open access: yesDrug Testing and Analysis, EarlyView.
Betamethasone concentrations in 20 horses from Japan and Germany following IV, IM, and INJ administration of betamethasone phosphate were analyzed using population pharmacokinetic modeling. For IV administration of 0.04 mg/kg q24 h, IPC and IUC were 0.012 and 0.31 ng/mL, respectively; the IUC approximated the IFHA urine ISL (0.20 ng/mL).
Taisuke Kuroda   +9 more
wiley   +1 more source

Impact of Drone Versus Car Transport on Anti‐Doping Sample Integrity Over Short Distances: A Proof‐Of‐Concept Study

open access: yesDrug Testing and Analysis, EarlyView.
This proof‐of‐concept study evaluated the impact of short‐distance drone transport on anti‐doping sample integrity compared with traditional car transport. Targeted assays and untargeted metabolomics revealed equivalent biological profiles between methods, confirming that drone delivery preserves sample integrity for the athlete biological passport ...
I. Al‐Mohannadi   +13 more
wiley   +1 more source

Simultaneous Detection of Steroid Esters and Multi‐Class Substances in Dried Blood Spots by LC‐HRMS/MS From a Single Spot for Human Doping Control

open access: yesDrug Testing and Analysis, EarlyView.
A validated LC‐HRMS/MS method enabled, for the first time, the comprehensive detection of steroid esters and multi‐class menu substances from a single dried blood spot. Following extraction, the resulting extract is split into two aliquots, reducing sample consumption and simplifying the analytical workflow.
Panagiotis Sakellariou   +4 more
wiley   +1 more source

Integrative Genomic and Functional Investigation of the Multi‐Layered Genetic Architecture Between Anorexia Nervosa and Bone Loss

open access: yesInternational Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Bone loss is a severe and often irreversible complication of anorexia nervosa (AN), yet the genetic mechanisms underlying this comorbidity remain underexplored. This study focuses on constructing a comprehensive genetic architecture between AN and estimated calcaneal bone mineral density (eBMD).
Tao Han   +14 more
wiley   +1 more source

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