Results 211 to 220 of about 183,996 (311)

Recent Advances (2023–2025) of Capillary Electrophoresis‐Mass Spectrometry (CE‐MS) for Top‐Down Proteomics

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT Top‐down proteomics (TDP) characterizes proteoforms in cells, tissues, and biofluids, in discovery mode and on a global scale, requiring analytical tools with high peak capacity for proteoform separation and high sensitivity for proteoform detection, given the extremely high proteoform complexity and wide proteoform concentration dynamic range.
Guijie Zhu   +5 more
wiley   +1 more source

Recent Advances in Top‐Down Proteomics for Single‐Cell Research

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT Individual cells have distinctive molecular characteristics, including biologically relevant proteoforms. Although single‐cell (SC) molecular omics offer unprecedented insights into cellular heterogeneity and function, the characterization of proteoforms in SCs remains an uncharted territory.
Jake A. Melby, Pei Su, Fabio P. Gomes
wiley   +1 more source

Investigating Intraspecific Attacks in Brown Bears (<i>Ursus arctos</i>) Using a Forensic Approach: Evidence from Northern Italy. [PDF]

open access: yesAnimals (Basel)
Marchetti C   +6 more
europepmc   +1 more source

Ferroptosis and Its Emerging Role in Gestational Diabetes Mellitus

open access: yesMedicine Advances, EarlyView.
Ferroptosis contributes to the development of gestational diabetes mellitus (GDM) through iron overload, lipid peroxidation, and antioxidant system disruption. These changes impair adipocyte and β‐cell function, promoting insulin resistance and hyperglycemia.
Jinfeng Xu   +4 more
wiley   +1 more source

The Impact and Reliability of Tissue Segmentation on In Vivo Magnetic Resonance Spectroscopy Metabolite Quantification

open access: yesMagnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Quantification of metabolite concentrations using MRS requires tissue‐dependent signal corrections. Accurate estimation of voxel tissue composition is therefore essential. Commonly used brain tissue segmentation tools differ in their algorithms and implementation, potentially introducing variability in MRS‐derived concentration ...
Jessica Archibald   +12 more
wiley   +1 more source

Anatomical Variant or Pathological Anomaly? A Case Report of an Asymptomatic Cardiac Apical Cleft. [PDF]

open access: yesInt Med Case Rep J
Posite CM   +8 more
europepmc   +1 more source

A Smile From the Past: Exploring a Fixed Bone Dental Bridge From Eighteenth/Nineteenth Century Porto (Portugal)

open access: yesInternational Journal of Osteoarchaeology, EarlyView.
ABSTRACT This paper presents the first documented case of a fixed bone dental bridge in Portugal. This item was recovered alongside the remains of a young adult individual of indeterminate sex from the 19th century burial site of the 3rd Order of Our Lady of Carmo in Porto, Portugal.
Steffi Vassallo   +8 more
wiley   +1 more source

Mechanophilia - a case report of a specific fetishistic disorder. [PDF]

open access: yesFront Psychiatry
Osvath P   +3 more
europepmc   +1 more source

Audio‐guided exercise at home: Preliminary findings from a pilot study on physical activity for people with low vision

open access: yesPM&R, EarlyView.
Abstract Background: Individuals with severe visual impairments frequently refrain from regular physical activity due to multiple barriers, including transportation difficulties, financial constraints, and limited availability of exercise programs tailored to their needs. These factors often contribute to a gradual decline in mobility and independence.
Luca Correale   +7 more
wiley   +1 more source

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