Results 41 to 50 of about 182,365 (307)

Examination of Methylation Sites for Forensic Age Determination from Semen [PDF]

, 2018
Methylation Sensitive High-Resolution Melt (MS-HRM) is based on quantitating the melt curve from an experimental sample against a standard of known methylation levels.
Renwick, Christian, Seashols-Williams, Sarah J.   +1 more
core   +1 more source

High‐Fidelity Synthetic Data Replicates Clinical Prediction Performance in a Million‐Patient Diabetes Cohort

Advanced Science, EarlyView.
This study generates high‐fidelity synthetic longitudinal records for a million‐patient diabetes cohort, successfully replicating clinical predictive performance. However, deeper analysis reveals algorithmic biases and trajectory inconsistencies that escape standard quality metrics. These findings challenge current validation norms, demonstrating why a
Francisco Ortuño, Víctor M. de la Oliva Roque, Javier‐Ignacio Ramirez‐Lopez, David P. Kreil, Joaquín Dopazo, Carlos Loucera   +5 more
wiley   +1 more source

ACSL1‐Dependent Microglial Lipoimmunometabolic Reprogramming Underlies Cognitive Deficits in Alcohol Use Disorder

Advanced Science, EarlyView.
This study reveals that chronic alcohol exposure selectively upregulates ACSL1 expression in prefrontal cortical microglia, driving lipid metabolism reprogramming and lipid droplet accumulation, which activates the NLRP3 inflammasome and sustains neuroinflammation. To reverse this process, a dual‐targeted lipid nanoparticle, siACSL1@LNP‐MR, is designed
Liang Hao, Xing‐Rui Cao, Bai‐Qiang Li, Fu‐Ying Zhao, Jia‐Mei Wang, Rui‐Kang Gao, Zhi‐Peng Cao, Zhen‐Xian Du, Hua‐Qin Wang   +8 more
wiley   +1 more source

Predict of the development of lipid distress syndrome in patients with a sustained response to antiviral therapy of chronic hepatitis C

Журнал инфектологии, 2019
The aim. is to develop a method, for predicting the development of lipid, distress syndrome in patients with a sustained, response to antiviral therapy of chronic viral hepatitis C on the basis of clinical and laboratory data.Materials and. methods.
D. Yu. Konstantinov, G. V. Nedugov
doaj   +1 more source

Forensic Examination as a Mediation Tool: Genesis and Prospects for Development in the Context of Martial Law and Post-War Revival of Ukraine

Studia Iuridica Lublinensia, 2023
The study explores justice, forensic examination and mediation from the time of their genesis to the present day. The article analyzes historical examples of the application of forensic examination within the mediation process from the Ancient East and ...
Vladislav L. Fedorenko, Volodymyr Kravchuk, Anton Demchuk, Tetiana Fedorenko   +3 more
doaj   +1 more source

There Is No Place Like Home: The Body as the Scene of the Crime in Sexual Assault Intervention [PDF]

, 2008
The body is the scene of the crime, is an oft-repeated phrase among nurses conducting sexual assault forensic examinations. This instruction reminds nurses that the object under scrutiny, the sexually violated body, is the location and source of ...
Mulla, Sameena A.
core   +1 more source

Proving Genocide? Forensic Expertise and the ICTY [PDF]

, 2008
This article works towards developing a theoretical framework outlining the premises and parameters under which forensic experts operate during various stages of international criminal investigations and the presentation of expert witness testimony in ...
Klinkner, Melanie Josefine
core   +1 more source

Inactivation Rap2a in Endothelial Cell Prevents Pulmonary Fibrosis by Regulating Immune Microenvironment Through MAP4K4‐VCAM1 Signaling

Advanced Science, EarlyView.
We identified the endothelial RAP2A as a regulator of inflammatory endothelial activation in experimental lung fibrosis and suggest that targeting RAP2A‐mediated signaling may represent a potential strategy to modulate endothelial–immune crosstalk during fibrotic lung injury.
Xiaolan Zheng, Peng Yue, Kaiyu Zhou, Guidong Gong, Yue Zhang, Sha Lin, Xu Liu, Yanjiang Zheng, Siyuan Jing, Junling Guo, Yan Qi, Bi‐Sen Ding, Yimin Hua, Yifei Li   +13 more
wiley   +1 more source

GENDER DIFFERENCES IN R CORRELATION CERTAIN CRANIOMETRIC CHARACTERISTICS

Известия высших учебных заведений. Поволжский регион: Медицинские науки, 2020
the science discussion in 1990s. The discovering of statistical pattern in craniological features characteristics, different for male and female skulls, was the goal of the study. Materials and methods.
A. B. Gasanov, A. Sh. Ibragimov, Z. M. Kerimov, I. N. Chairkin, N. L. Shepetovskaya, E. V. Kondyurova   +5 more
doaj   +1 more source