Results 71 to 80 of about 9,621 (267)

A Perspective of Multi‐Reflecting TOF MS

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Time‐of‐flight mass spectrometry (TOF MS) excels in rapid and high‐sensitivity analysis, making it a cornerstone of analytical chemistry. But as sample complexity explodes in omics studies, so does the need for higher resolving power to ensure accurate results.
A. N. Verenchikov, V. V. Makarov, A. V. Vorobyev, S. N. Kirillov   +3 more
wiley   +1 more source

Antithrombin: Deficiency, Diversity, and the Future of Diagnostics

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Our healthcare system provides reactive sick‐care, treating patients after symptoms have appeared by prescription of generic and often suboptimal therapy. This strategy brings along high costs and high pressure which is not sustainable.
Mirjam Kruijt, Christa M. Cobbaert, L. Renee Ruhaak   +2 more
wiley   +1 more source

The Tasks of Forensic Vehicle Inspections

Теория и практика судебной экспертизы, 2019
Theoretical provisions concerning the subject of forensic vehicle inspections, their objects and tasks, investigatory techniques are still not developed in forensic and expert literature.
N. N. Il’in
doaj   +1 more source

Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research

Mass Spectrometry Reviews, EarlyView.
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik, Petr Lapcik, Pavla Bouchalova, Pavel Bouchal   +3 more
wiley   +1 more source

Proteomics of Nitrotyrosine: Integrating Mass Spectrometry and Immunodetection in Redox‐Driven Pathology

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Nitrooxidative stress, driven by excess reactive nitrogen species like peroxynitrite, contributes to the pathogenesis of many chronic diseases. Among its molecular footprints, 3‐nitrotyrosine (3NT) has emerged as a biologically relevant marker of protein nitration.
Brîndușa Alina Petre
wiley   +1 more source

Reliability of Species Assessment of Archaeological Cremated Bone Fragments: Confidence in Diagnosis and Interobserver Agreement

International Journal of Osteoarchaeology, EarlyView.
ABSTRACT The ancient practice of cremation has been documented across numerous cultures, yet burnt remains can indeed become a huge challenge for anthropologists, both in archaeological and in forensic contexts. The analysis of such skeletal material presents significant challenges associated with the alterations caused by the process of burning.
Carlotta Sala, Marco Cummaudo, Debora Mazzarelli, Giulia Caccia, Marta Mondellini, Fabrizio Slavazzi, Cristina Cattaneo   +6 more
wiley   +1 more source

Modern view on potentials of forensic pharmaceutical and pharmacological expertise

Journal of Forensic Science and Medicine
The great number of drugs and their variety have increased the potential of therapy but increased the risks of crimes related to the production, sale, and use of medicines.
Elena M Vazhnichaya, Nataliia M Deviatkina   +1 more
doaj   +1 more source

Clinicopathological characteristics of patients with inoperable non‐small cell lung cancer harboring circulating NRF2 pathway mutations

The Journal of Pathology, EarlyView.
Abstract Lung cancer is the leading cause of global cancer‐related morbidity and mortality, with tobacco smoking as its strongest risk factor. Nuclear factor erythroid 2‐related factor 2 (NRF2) is a redox‐regulated transcription factor frequently dysregulated in non‐small cell lung cancer (NSCLC), leading to aggressive disease and resistance to therapy.
Jouni Härkönen, Satu Tiainen, Jouni Kujala, Linnea Muhonen, Ponnuswamy Mohanasundaram, Tuomas Tikkanen, Ina Pöhner, Tommi Patinen, Simone Adinolfi, Juha P Väyrynen, Päivi Auvinen, Arto Mannermaa, Petri Pölönen, Tuomas Rauramaa, Anna‐Liisa Levonen   +14 more
wiley   +1 more source

Digitizing collections to unlock the full potential of palynology: A case study with the Smithsonian palynology collection

PLANTS, PEOPLE, PLANET, EarlyView.
Large palynological collections have been built over decades and contain vital information. However, they are often difficult to access and use effectively. What is the point of having such collections if they are not fully utilizable? To solve this problem, we digitized the Smithsonian palynological collection using both light and confocal microscopy.
Carlos Jaramillo, Surangi W. Punyasena, Daurys de Alba, Roxana Alveo, Angelica Arcila, Jorge Bermudez, Jonatan Bustos, Dayenari Caballero‐Rodriguez, Karen Cardenas, David Caro, Francy Carvajal, Ivonne Marcela Castañeda, Shara Chaves, Carlos D'Apolito, Andres Diaz‐Jaramillo, Laura Diaz, Luisa Gomez, Mauricio León‐Carreño, Paula Lopera, Maria Alejandra Lopez, Priscila Lopez, Luke Mander, Jhonatan Martínez Murcia, Carlos Moreno, Enrique Moreno, Enrique Neyra, Brenda Orosco, Jhon Ortiz, Natalia Ossa, Natalia Ovalle, Carolina Ovalle, Angelo Plata, Ingrid Romero, Bruno Scudeiro, Silane A. F. da Silva Caminha, Axel Tejada‐Fajardo, Vinicius Do Valle, Thiago Wood   +37 more
wiley   +1 more source

Using MALDI‐FTICR Mass Spectrometry to Enhance ZooMS Identifications of Pleistocene Bone Fragments Showing Variable Collagen Preservation

Rapid Communications in Mass Spectrometry, EarlyView.
ABSTRACT Rationale Recent advances in high‐throughput molecular analyses of collagen peptides, especially ZooMS (Zooarchaeology by Mass Spectrometry), have permitted breakthroughs in the analysis of archaeological material that is highly fragmented, a factor that hinders morphological identification.
Pauline Raymond, Karen Ruebens, Fabrice Bray, Jean‐Christophe Castel, Eugène Morin, Foni Le Brun‐Ricalens, Jean‐Guillaume Bordes, Christian Rolando, Jean‐Jacques Hublin   +8 more
wiley   +1 more source