Results 191 to 200 of about 100,106 (260)
What anabolic–androgenic steroids reveal about the limits of current harm reduction models
Addiction, EarlyView.Abstract Background Harm reduction has largely been shaped by responses to psychoactive drug use where the most urgent harms are acute. These models focus on overdose, blood‐borne viruses, and rapid‐onset toxicity related harms. When applied wholesale to anabolic–androgenic steroids (AAS), they obscure the distinctive pharmacology, consumer typologies,
Timothy Piatkowski +2 more
wiley +1 more source
“And then I got strangled”: Dangerous trends of sexual choking among young people
Acta Obstetricia et Gynecologica Scandinavica, EarlyView.Sexual choking is increasingly normalized among young people yet is never medically safe; loss of consciousness can occur within seconds, making consent impossible to verify. Clinicians should routinely ask about choking, assess injuries, and counsel patients against breath‐control practices.
Katja Kero, Hannu Lauerma, Pia Wahlsten
wiley +1 more source
Bilateral Supracondylar Process in a Subadult in the Late Antique Age: A Case Report
Archaeometry, EarlyView.ABSTRACT During the excavation procedures for the railway trait Napoli‐Cancello, in the city of Afragola (Naples), several burials dating back to the Late Antique Age were found. One of them was an amphora burial (enchytrismòs) and contained the skeletal remains of a subadult individual affected by bilateral supracondylar process. Supracondylar process
Barbara Albanese +3 more
wiley +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aims Since their emergence on the drug market, synthetic cannabinoids (SC) are still gaining increasing importance in forensic toxicology. The representatives of the so‐called new psychoactive substances have in common that they have not undergone preclinical safety studies. Hence, knowledge on toxicokinetic (TK) data is sparse.
Adrian A. Doerr +10 more
wiley +1 more source
Business Ethics, the Environment &Responsibility, EarlyView.ABSTRACT This paper examines whether managers of socially responsible firms strategically manage the tone of disclosure across different communication channels, with a focus on Management Discussion and Analysis (MD&A) and Corporate Social Responsibility (CSR) reports.
Sibei Yan +3 more
wiley +1 more source
British Journal of Clinical Psychology, EarlyView.Abstract Objectives We aimed to investigate the developmental trajectories of social responsiveness and theory of mind (ToM) from childhood to adolescence in offspring at familial high risk of schizophrenia (FHR‐SZ) or bipolar disorder (FHR‐BP) and population‐based controls (PBC).
Lotte Veddum +16 more
wiley +1 more source
The DNA/RNA autophagy protein SIDT2 as a novel neuropathological hallmark in Huntington disease
Brain Pathology, EarlyView.SIDT2‐immunoreactive inclusions are observed in the striatum, cerebral cortex, and hypothalamus in HD cases with different Vonsattel grades, and the frequency of SIDT2‐immunoreactive inclusions is associated with longer CAG repeats in the huntingtin gene.
Sanaz Gabery +17 more
wiley +1 more source
Associations between TMEM106B C‐terminal fragment aggregation, age, and TDP‐43 or tau pathology
Brain Pathology, EarlyView.TMEM106B C‐terminal fragment (CTF) aggregation represents an age‐associated, common, diffuse phenomenon emerging after midlife with a weak association with TDP‐43 or tau pathology. These findings suggest that TMEM106B fibrillization may define a distinct axis of protein aggregation in the aging human brain. Abstract Transmembrane protein 106B (TMEM106B)
Albert Acewicz +5 more
wiley +1 more source
British Journal of Pharmacology, EarlyView.Abstract Background and Purpose Ketone bodies are liver‐derived circulating energy metabolites that positively impact most hallmarks of ageing. Ketone bodies increase during calorie restriction and fasting, two of the more widely perceived methods to increase health span.
Tábata Bergonci +15 more
wiley +1 more source