Results 61 to 70 of about 81,679 (340)

Forensic Lung Pathology [PDF]

, 2008
Sudden and unexpected natural deaths and nonnatural deaths may result from various pulmonary conditions. Additionally, several nonpulmonary conditions of forensic significance may be complicated by the development of respiratory lesions. Certain situations with pulmonary pathology are particularly likely to be critically scrutinized and may form the ...
openaire   +1 more source

SIRT6 Lysine‐Demyristoylates ATF2 to Ameliorate Vascular Injury via PRKCD/VE‐Cadherin Pathway Regulating Vascular Endothelial Barrier

Advanced Science, EarlyView.
A novel modified SIRT6 variant (dSIRT6) H133Y‐mediated enrichment technique unmasks 15 new human lysine‐myristoylated proteins. Notably, Sirtuin 6 (SIRT6) demyristoylation of activating transcription factor 2 (ATF2) at K296 orchestrates its nucleoplasmic translocation.
Runyang Feng, Zheyan Fang, Shuang Zhao, You‐en Zhang, Na Wu, Zhenyang Guo, Xin Zhong, Bixuan Jiang, Hongfei Xu, Hangnan Hong, Zhentao Zhang, Mukaddas Abdurahman, Xueting Yu, Jilong Geng, Xiansu Nie, Supuya Abuduwahapi, Dong Huang, Gang Zhao, Wenbin Zhang, Hao Lu, Li Shen, Xin Zhao, Zhaoyang Chen, Junjie Guo, Hongchao Zheng, Yue He, Sanwu Wu, Jiayin Peng, Jiawen Song, Xiao Wang, Haomin Li, Yuli Huang, Shengying Qin, Haojie Lu, Xiangdong Wang, Jianguo Zhao, Lei Huang, Yun Zhao, Peng Li, Junbo Ge, Hua Li   +40 more
wiley   +1 more source

Methamphetamine Disturbs Gut Homeostasis and Reshapes Serum Metabolome, Inducing Neurotoxicity and Abnormal Behaviors in Mice

Frontiers in Microbiology, 2022
As an illicit psychostimulant, repeated methamphetamine (MA) exposure results in addiction and causes severe neurotoxicity. Studies have revealed complex interactions among gut homeostasis, metabolism, and the central nervous system (CNS). To investigate
Kai-Kai Zhang, Li-Jian Chen, Jia-Hao Li, Jia-Li Liu, Li-Bin Wang, Ling-Ling Xu, Jian-Zheng Yang, Xiu-Wen Li, Xiao-Li Xie, Qi Wang   +9 more
doaj   +1 more source

Evaluating elbow osteoarthritis within the prehistoric Tiwanaku state using generalized estimating equations (GEE). [PDF]

, 2019
OBJECTIVES:Studies of osteoarthritis (OA) in human skeletal remains can come with scalar problems. If OA measurement is noted as present or absent in one joint, like the elbow, results may not identify specific articular pathology data and the sample ...
Bass W. M., Brothwell D. R., Buikstra J. E., Dieppe P., Felson D., Gagnon C. M., Gagnon C. M., Goldstein P. S., Goldstein P. S., Goodman A. H., Hunter D., Iscan M. Y., Janusek J. W., Jurmain R., Krogman W., Pearson O. M., Rogers J., Suchey J. M., Suchey J. M., Ubelaker D. H., Verano J., White T. D.   +21 more
core   +1 more source

Targeting ROCK2 to Restore Epileptic Synaptic Networks via Mitophagy Activation: Insights from Translational Imaging of SV2A In Vivo

Advanced Science, EarlyView.
By integrating synaptic vesicle glycoprotein 2A PET imaging and transcriptomics, this study identifies Rho‐associated protein kinase 2 (ROCK2) as a critical regulator of synaptic network dysfunction in temporal lobe epilepsy. Pharmacological ROCK2 inhibition restores synaptic density and enhances mitophagy, thereby reducing seizures and neuronal damage.
Ling Xiao, Jing Wang, Bei Chen, Jinhui Yang, Fangyu Wu, Chunyao Zhou, Yifei Zhang, Zhiquan Yang, Dingyang Liu, Lei Tian, Jianhua Yu, Fei Han, Yongxiang Tang, Li Feng, Shuo Hu   +14 more
wiley   +1 more source

Forensic Pathology of Society-Oriented Expert Identification Institutions in China: A Retrospective Study by 11-year Data from Academy of Forensic Science

Journal of Forensic Science and Medicine
Objective: The aim of the study was to introduce the development of forensic pathology for social-oriented forensic-identification institutions, using the Academy of Forensic Science as an example.
Yuan-Yuan Liu, En-Hao Fu, Ya-Wen Liu, Dong-Hua Zou, Jiang Huang, Hao-Jie Qin, Ning-Guo Liu   +6 more
doaj   +1 more source

Analysis of the autopsy, toxicological, and psychiatric reports of Portugal’s first major forensic case: part III

Forensic Sciences Research, 2021
This work presents an odd historical record obtained through more than 14 years of research regarding one of the first major European forensic cases. The presumed homicide of Mário Guilherme Augusto de Sampaio in 1890 was allegedly perpetrated by his ...
Ricardo Jorge Dinis-Oliveira
doaj   +1 more source

Microbial communities in the liver and brain are informative for postmortem submersion interval estimation in the late phase of decomposition: A study in mouse cadavers recovered from freshwater

Frontiers in Microbiology, 2022
IntroductionBodies recovered from water, especially in the late phase of decomposition, pose difficulties to the investigating authorities. Various methods have been proposed for postmortem submersion interval (PMSI) estimation and drowning ...
Linlin Wang, Linlin Wang, Fuyuan Zhang, Kuo Zeng, Wenwen Dong, Wenwen Dong, Huiya Yuan, Huiya Yuan, Ziwei Wang, Jin Liu, Jiaqing Pan, Rui Zhao, Rui Zhao, Dawei Guan, Dawei Guan   +14 more
doaj   +1 more source

Towards a working methodology for using total hip and knee joint replacements to support identification [PDF]

, 2015
Hip and knee prostheses have occasionally been used to support identification of unknown persons along with other medical devices and implants. This paper looks at the specific issues around using hip and knee implants, suggesting a working methodology ...
Bryson, David
core   +1 more source

Understanding Youth Assaults of Police Officers in Australia: A Power Threat Meaning Framework Analysis

Australian Journal of Social Issues, EarlyView.
ABSTRACT This study explores youth violence towards police officers in Australia through the Power Threat Meaning Framework (PTMF) to better understand the underlying factors contributing to such violence; focusing on power dynamics, childhood adversity, and trauma.
Dimitra Lattas, Kelly Hine, Catherine Creamer, Kelley Burton, Katelyn Davenport‐Klunder   +4 more
wiley   +1 more source