Results 191 to 200 of about 39,287 (277)

Bioactivation and Metabolism of Amino Acid MDMA Prodrugs in Zebrafish Embryos, Human Liver S9, Whole Blood, and Microdosed Human Urine

open access: yesDrug Testing and Analysis, Volume 18, Issue 5, Page 669-677, May 2026.
Bioactivation and metabolism of MDMA prodrugs: MDMA‐Trp, MDMA‐Lys, MDMA‐Gly showed unique urine screening targets only for MDMA‐Trp, while biomarkers for MDMA‐Lys and MDMA‐Gly consisted of MDMA and known MDMA metabolites. Conversion of amino acid prodrugs to MDMA in pHLS9, zebrafish embryos, and humans. ABSTRACT 3,4‐Methylenedioxymethamphetamine (MDMA)
Simon K. Wellenberg   +6 more
wiley   +1 more source

Risk Stratification in Pulmonary Embolism: Prognostic Value of PESI, WELLS, PADUA, and IMPROVE Scores in Relation to Laboratory Markers. [PDF]

open access: yesJ Clin Med
Crisan DN   +9 more
europepmc   +1 more source

Evaluation of Different Detection and Identification Methods of Intact Tetrahydro‐Methyltestosterone Sulfate Metabolites in Doping Control

open access: yesDrug Testing and Analysis, Volume 18, Issue 5, Page 678-689, May 2026.
The micro‐scale synthesis of the six out of eight possible tetrahydro‐methyltestosterone sulfate metabolites was performed, and the synthesized materials were used as analytical standards. The analysis of post‐administration sample extracts from methyltestosterone excretion studies against these standards provides further experimental proof for their ...
Yiannis S. Angelis   +3 more
wiley   +1 more source

Association of Genetic Polymorphisms with Ischemic Sudden Cardiac Death: A Comparative Case-Control Study in North-Western Transylvania (Romania). [PDF]

open access: yesBiomedicines
Pavel Mironescu DC   +12 more
europepmc   +1 more source

Unlocking the Hepatoprotective Potential of Cyperus rotundus Through Edible Vinegar Processing: A Study on Functional Ingredient Enhancement

open access: yesFood Science &Nutrition, Volume 14, Issue 5, May 2026.
Cyperus rotundus L. (CR) and vinegar‐processed CR (VCR) were compared in mouse models of thioacetamide (TAA)‐induced acute and chronic liver injury. VCR exhibited better hepatoprotective effects than raw CR. Composition analysis revealed 35 components in VCR, among which α‐cyperone was present at higher levels than in raw CR.
Gao Jia‐He   +5 more
wiley   +1 more source

Forensic Identification through Denture Tags: Performance under Stimulated Environmental Conditions. [PDF]

open access: yesJ Pharm Bioallied Sci
Patel D   +6 more
europepmc   +1 more source

Underprescription of Clozapine: A Narrative Review Regarding ‘Clozaphobia’

open access: yesHuman Psychopharmacology: Clinical and Experimental, Volume 41, Issue 3, May 2026.
ABSTRACT This review aims to examine the appropriateness of the term ‘clozaphobia’ to characterise the obstacles contributing to the underprescription of clozapine (CLZ). English‐language, peer‐reviewed studies addressing clinicians', patients' and/or carers' attitudes toward CLZ were considered eligible for full‐text review.
Rafael Brito Castro   +2 more
wiley   +1 more source

High‐Throughput N‐Glycan Analysis by IR‐MALDESI With a 1.5‐kHz Pulsed Mid‐IR Laser

open access: yesJournal of Mass Spectrometry, Volume 61, Issue 5, May 2026.
ABSTRACT Infrared matrix‐assisted laser desorption electrospray ionization (IR‐MALDESI) is a laser‐based, hybrid ionization source for mass spectrometry, enabling both mass spectrometry imaging (MSI) and high‐throughput screening (HTS). In this work, a 2.2‐ns, 2.72‐μm laser, operating at 1.5 kHz, was integrated into the IR‐MALDESI platform to evaluate ...
Seth M. Eisenberg   +5 more
wiley   +1 more source

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