Results 51 to 60 of about 39,287 (277)

A Novel Workflow for Fast Elucidation of Drug Metabolites for Screening—Combining In Silico Metabolite Prediction With Trapped Ion Mobility QTOF‐MS

open access: yesDrug Testing and Analysis, EarlyView.
UHPLC‐timsTOF‐MS with in silico prediction and automated annotation enabled rapid identification of quetiapine metabolites from pHLMs, facilitating their inclusion in targeted LC‐QTOF‐MS urine screening and improving biomarker detection for toxicological applications.
Annette Zschiesche   +5 more
wiley   +1 more source

Effect of Reaction Time and Temperature on the Impurity Profile of Amphetamine in the Leuckart Method

open access: yesDrug Testing and Analysis, EarlyView.
This study investigates the effect of the reaction temperature (step 1) and reaction time (step 1 and 2) on the conversion efficiency and impurity profile of amphetamine synthesized via the Leuckart method. Conversion efficiency and impurity profile were assessed using gas chromatography–flame ionization detection (GC–FID) and GC–mass spectrometry (GC ...
Maartje C. M. Verhoeven   +7 more
wiley   +1 more source

Organization of availability of the circulation of antidiabetic medicines based on pharmaceutical law in Ukraine

open access: yesAnnals of Mechnikov's Institute, 2020
Introduction. In recent years as the global problem of healthcare in many countries acts diabetes, number of patients with this disease is growing and is already 4-6% of the population in developed countries.
S Zbrozhek   +2 more
doaj  

Green-Extraction Methodologies for Recovering Bioactive Compounds from Endemic Fruits: Corcolen (Azara dentata)

open access: yesBiology and Life Sciences Forum, 2022
There is a great demand for the recovery of bioactive compounds from by-products and side streams in the food and cosmetic industries. More sustainable extraction methodologies are being chosen, such as pulsed electric field (PEF) assisted extraction ...
Lucia Cuesta Ramos   +6 more
doaj   +1 more source

Positive Doping Test Linked to Crumb Rubber From Artificial Football Pitch: Case Report

open access: yesDrug Testing and Analysis, EarlyView.
1,3‐DMBA was detected in urine samples of eight athletes following a doping control, resulting in one AAF and levels below WADA's MRL in seven teammates. Investigation revealed contamination from rubber infill used on the indoor artificial turf, with analysis confirming 1,3‐DMBA in the turf's crumb rubber originating from recycled tires.
Astrid Gjelstad   +7 more
wiley   +1 more source

In Vivo and In Vitro Evaluation of PTeCA (1H‐Pyrrole‐2,3,4,5‐Tetracarboxylic Acid) in Hair Matrix as a Marker for Oxidative Cosmetic Treatment

open access: yesDrug Testing and Analysis, EarlyView.
A total of 3378 self‐reported treated and untreated hair samples were analyzed for PTCA and PTeCA by LC‐MS/MS. Moreover, their in vitro formation was assessed in 225 untreated hair by different cosmetic treatments with and without oxidative agents. Data suggest that PTeCA could be a reliable marker for oxidative cosmetic treatments in hair.
Sara Casati   +8 more
wiley   +1 more source

Simultaneous Determination of Selegiline, Desmethylselegiline, R/S-methamphetamine, and R/S-amphetamine on Dried Urine Spots by LC/MS/MS: Application to a Pharmacokinetic Study in Urine

open access: yesFrontiers in Chemistry, 2019
Objective: Chiral analysis is a crucial method to differentiate selegiline intake from drug abuse. A dried urine spot (DUS) analytical method based on spotting urine samples (10 μL) onto dried spot collection cards, and followed by air-drying and ...
Lizhu Chen   +6 more
doaj   +1 more source

Health of children and young people in secure settings [PDF]

open access: yes, 2007
This small-scale descriptive study was commissioned by the Children and Young People's Public Health team within the Department of Health, in partnership with Offender Health, in order to inform preparation and implementation of an Offender Health ...
Mooney, Ann, Statham, J, Storey, P
core   +1 more source

Mental health services in Nepal: Is it too late? [PDF]

open access: yes, 2015
Mental health has historically been neglected both in the developed and developing world. It was not included in the Millennium Development Goals, the global targets for the developing world’s fight towards better health and development.
Marahatta, S. B.   +2 more
core   +1 more source

Chemical Straightening as a Source of Analytical Variability in Hair Testing: A Dual‐Analyte Case Report

open access: yesDrug Testing and Analysis, EarlyView.
ABSTRACT Hair analysis is increasingly used in forensic toxicology; however, result interpretation may be influenced by cosmetic hair treatments. Although the effects of bleaching, dyeing, and thermal straightening have already been evaluated, data on permanent chemical hair straightening are scarce, particularly under in vivo conditions.
Miriam Blanco‐Ces   +5 more
wiley   +1 more source

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