Results 91 to 100 of about 70,147 (264)

In Vitro Metabolism of Δ8‐, Δ9‐, and Δ10‐THC in Human Hepatocytes: Distinct Δ10‐THC Biotransformation and Implications for Drug Testing

open access: yesDrug Testing and Analysis, EarlyView.
Δ8‐THC and Δ9‐THC showed comparable metabolic profiles. In contrast, Δ10‐THC underwent extensive glucuronidation and hydroxylation, with only minor formation of a carboxy metabolite, indicating a markedly different metabolic pathway. These differences may increase the risk of misidentification and misinterpretation in cannabis drug testing.
Robert Kronstrand   +4 more
wiley   +1 more source

Investigations Into the Metabolism and Elimination of Tesofensine in Human Urine

open access: yesDrug Testing and Analysis, EarlyView.
This study investigated tesofensine metabolism and urinary elimination after a single 483 μg intake via a dietary supplement. In six volunteers, urine was collected up to 659 h. LC‐HRMS/MS identified four tentative metabolites; maximum urinary concentrations reached 4 ng/mL within 4–48 h.
O. Krug, A. Thomas, M. Thevis
wiley   +1 more source

Identification of Synthetic Urine by Analysis of Stable Carbon and Nitrogen Isotope Ratios and Comparison to Established GC‐MS/MS and LC‐MS/MS Analysis

open access: yesDrug Testing and Analysis, EarlyView.
This study compared GC‐MS/MS, EA‐IRMS, and LC‐MS/MS for detecting synthetic and manipulated urine samples in doping control and forensic analysis. EA‐IRMS proved particularly effective for identifying mixtures of synthetic and authentic urine, providing a reliable complement to established authenticity testing methods.
Frank Hülsemann   +4 more
wiley   +1 more source

Detection of Testosterone Esters in Urine: Evidence of Trace‐Level Detectability in Doping Control Samples

open access: yesDrug Testing and Analysis, EarlyView.
An ultrasensitive LC‐MS/MS method for detecting testosterone esters (T‐esters) in urine at sub–pg/mL levels is presented. This approach, employing Girard P derivatization, provides the first evidence of T‐esters' trace‐level detectability in human urine.
Daniel Pecher   +3 more
wiley   +1 more source

Reproducibility of Serum Androgen Concentrations by Liquid Chromatography Mass Spectrometry in Healthy Male and Female Athletes

open access: yesDrug Testing and Analysis, EarlyView.
Box and whiskers plots show the distributions of serum testosterone (T), dihydrotestosterone (DHT), androstenedione (A4), and the ratios of T/FDHT and T/A4. ABSTRACT Detection of androgen doping relies on mass spectrometry‐based methods to detect natural endogenous and exogenous androgens in urine and serum. To distinguish exogenous administration from
D. J. Handelsman, S. Bermon
wiley   +1 more source

The Design and Development of a Survey Instrument to Measure Factors that Influence Choice Goals of Forensic Science Majors [PDF]

open access: yes, 2016
Colleges and universities are encouraged to strengthen forensic science programs to combat that shortage of highly educated and trained forensic scientists entering the field.
Steinmetz, Stacey
core  

Modeling and Output Optimization of Triboelectric Microphone for Acoustic Energy Harvesting

open access: yesENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
This work elucidates the fundamental multiphysics coupling mechanisms governing acoustic T‐phone, providing a critical theoretical foundation and a predictive design paradigm for the future engineering and deployment of next‐generation, self‐powered acoustic sensors.
Dan Liu   +6 more
wiley   +1 more source

Forensic science [PDF]

open access: yesForensic Science, 1972
openaire   +1 more source

The role of forensic geoscience in wildlife crime detection

open access: yes, 2006
The increase in both automation and precision in the analysis of geological materials has had significant impact upon forensic investigations in the last 10 years.
Morgan, RM   +3 more
core  

Development of Pentaplex Reverse Transcription Droplet Digital PCR Assay for Simultaneous Detection and Absolute Quantification of HIV‐1, HIV‐2, HCV, and HBV With Internal Control

open access: yesELECTROPHORESIS, EarlyView.
Development of Pentaplex reverse transcription droplet digital PCR assay for simultaneous detection and absolute quantification of HIV‐1, HIV‐2, HCV, and HBV with internal control. The channel‐resolved multiplex strategy enables high sensitivity, robust quantification, and scalable digital PCR workflows across platforms.
Soo Yeon Lim   +5 more
wiley   +1 more source

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