Results 181 to 190 of about 27,369,711 (294)

ER‐Localized Deadenylase PNLDC1 Suppresses Colorectal Cancer Progression by Targeting the mRNA Decay of TUBB4B

open access: yesExploration, EarlyView.
The deficiency of PNLDC1 exacerbates the advancement of CRC. PNLDC1 interacts with TUBB4B mRNA to regulate the p53–p21–CDK2–cyclin E2 pathway, thereby influencing the G2/M phase of the cell cycle. ABSTRACT Colorectal cancer (CRC) remains a leading cause of cancer‐related mortality, highlighting the urgent need for novel therapeutic strategies.
Lexin Liu   +18 more
wiley   +1 more source

Experimental and Numerical Investigation of Cedar Façade Flame Spread With Respect to Sidewall

open access: yesFire and Materials, EarlyView.
ABSTRACT In response to growing energy conservation and carbon neutrality efforts, façade systems incorporating wooden materials have attracted increasing attention, which in turn raises concerns about their combustibility. This study presents a combined experimental and numerical investigation of flame spread along cedar façades.
Xukun Sun   +6 more
wiley   +1 more source

Mechanical Behaviour of Vacuum‐Infused GFRP Composites at Elevated Temperatures—Influence of Fibre Architecture

open access: yesFire and Materials, EarlyView.
ABSTRACT This study addresses the influence of fibre architecture on the mechanical properties of vacuum‐infused glass fibre reinforced polymer (GFRP) composites at elevated temperatures (ET). Laminates with three different fibre configurations—unidirectional (UD), bidirectional 0°/90° cross‐ply (BD), and ±45° off‐axis angle‐ply (OA) – were tested in ...
Eloísa Castilho   +4 more
wiley   +1 more source

Char Layer Thickness Evolution During Structural Timber Fire Experiment and Final Density Profile

open access: yesFire and Materials, EarlyView.
ABSTRACT This paper evaluates several non‐destructive experimental methods for determining the char layer thickness and its density profile in structural timber samples exposed to standard ISO 834 fire curve experiments. Microwave echo pulse, ultrasonic echo pulse, X‐ray computed tomography, and resistance drilling were evaluated.
Fernando Pérez Pérez   +4 more
wiley   +1 more source

Hiring qualified Forensic Investigative Genetic Genealogy (FIGG) practitioners: Recommendations for forensic science and law enforcement agencies. [PDF]

open access: yesForensic Sci Int Synerg
McLean W   +9 more
europepmc   +1 more source

Influence of Adhesive Type on Heat Induced Delamination in Tension Loaded Shear Lap Cross‐Laminated Timber Samples Exposed to Radiant Heat Flux

open access: yesFire and Materials, EarlyView.
ABSTRACT Heat induced delamination (HID) is a phenomenon in engineered wood products which may result in the detachment of the bonded timber lamellae before charring propagates to the bond line interphase. This study aims to correlate the thermal degradation of two 1‐c‐polyurethane adhesives at the microscale to the thermo‐hydro‐mechanical behaviour of
A. Čolić   +4 more
wiley   +1 more source

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