Results 111 to 120 of about 10,701 (209)

A Single‐Aliquot Strategy for Simultaneous Carbon Isotope Confirmation of 6‐Oxo‐Androstenedione and Testosterone Misuse in Doping Control

open access: yesDrug Testing and Analysis, EarlyView.
This method enables simultaneous carbon isotope confirmation of 6‐oxo‐androstenedione and testosterone markers from a single urine aliquot, using bench‐top extraction, two preparative HPLC steps with intermediate acetylation, and GC/C/IRMS analysis. It was fully validated according to WADA requirements, and real samples demonstrated its fitness for ...
Fábio Azamor de Oliveira   +7 more
wiley   +1 more source

2026 Consensus for the Use of Alcohol Markers in Hair for Supporting the Assessment of Abstinence and Chronic Alcohol Consumption

open access: yesDrug Testing and Analysis, EarlyView.
The 2026 Society of Hair Testing (SoHT) Consensus recommends ethyl glucuronide (EtG) as the primary hair marker for supporting the assessment of alcohol abstinence and chronic excessive alcohol consumption. In proximal scalp hair, EtG ≤ 5 pg/mg does not contradict self‐reported abstinence, whereas EtG ≥ 30 pg/mg strongly suggests chronic excessive ...
Donata Favretto   +10 more
wiley   +1 more source

Potential Contamination Cases in Anti‐Doping: Experiences and Practices of 33 Anti‐Doping Organisations

open access: yesDrug Testing and Analysis, EarlyView.
Across 33 Anti‐Doping Organisations (ADOs), 85% reported experiencing at least one contamination‐claim case in 2024–2025, but only 36% operate a standardised process for handling such claims. Dietary supplements were the leading alleged contamination source (76% of ADOs), followed by food (42%) and pharmaceutical products, intimate contact, and other ...
Kristian Slíž   +2 more
wiley   +1 more source

Evidence for the Effectiveness of the Performance Passport Within an Intelligence‐Based Weightlifting Anti‐Doping Programme

open access: yesDrug Testing and Analysis, EarlyView.
Anti‐doping programmes require efficient testing, as biological testing is costly; the Athlete Performance Passport (APP) uses performance data to identify at‐risk athletes alongside APMU and ABP methods. Since the introduction of the steriodal passport in 2014, the APP outperformed APMU (17%) and ABP steroidal profiles (10%) with 30% detection ...
Gregory Hayward   +5 more
wiley   +1 more source

Population‐Stratified Distributions of Post‐Mortem Blood Drug Concentrations: An Epidemiological Framework for Contextual Interpretation

open access: yesDrug Testing and Analysis, EarlyView.
Post‐mortem blood drug concentrations exhibit substantial overlap between deaths in which a drug was implicated and those in which it was not. Analysis of over 58,000 NPSUM cases demonstrates that demographic stratification does not resolve this uncertainty, reinforcing the need for contextual, evidence‐based interpretation rather than concentration ...
Thikra Algahtani   +6 more
wiley   +1 more source

Retrospective Study on the Power and Interpretation of Chiral Amphetamine Analysis in Hair for Forensic Applications

open access: yesDrug Testing and Analysis, EarlyView.
A decision model for the interpretation of chiral amphetamine analysis in hair was established based on the enantiomeric fraction (EF) of (S)‐amphetamine in authentic hair samples. Two chiral analysis methods (indirect/direct) were consecutively applied to distinguish between illicit and therapeutic amphetamine use in forensic cases.
Liesl K. Janssens   +3 more
wiley   +1 more source

Intra‐Individual Variability of Blood and Urinary Steroid Markers and the Response to Codeine Intake in Healthy Men and Women

open access: yesDrug Testing and Analysis, EarlyView.
Short‐term codeine administration (1–3 days) caused individual alterations in Athlete Biological Passport steroid markers, including elevated urinary T/E ratios and decreased serum testosterone concentrations below individual thresholds, despite no significant changes at the group level.
Alexander Andersson   +5 more
wiley   +1 more source

The Role of Nitrous Oxide (“Laughing Gas”) in DUID Cases and Its Impact on Driving Fitness

open access: yesDrug Testing and Analysis, EarlyView.
A total number of 39 cases of driving under the influence of nitrous oxide were investigated. Plasma concentrations of 0.22 to 17 mL/L (median:3.7 mL/L) were measured in blood samples withdrawn 38 to 144 min (median: 85 min) after control via Headspace‐GC–MS.
L. Lucuta   +4 more
wiley   +1 more source

Integrative Genomic and Functional Investigation of the Multi‐Layered Genetic Architecture Between Anorexia Nervosa and Bone Loss

open access: yesInternational Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Bone loss is a severe and often irreversible complication of anorexia nervosa (AN), yet the genetic mechanisms underlying this comorbidity remain underexplored. This study focuses on constructing a comprehensive genetic architecture between AN and estimated calcaneal bone mineral density (eBMD).
Tao Han   +14 more
wiley   +1 more source

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