Results 41 to 50 of about 64,237 (306)

TME/NIR Dual‐Responsive Zinc‐Based Targeted Nanoagonist for Multimodal Amplification of STING‐Mediated Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
A multifunctional nanoagonist (cDZ@IP) enables nano‐metabolite–driven multimodal activation of the STING pathway and enhanced immune recognition, achieving potent antitumor immunity and suppressing tumor growth and metastasis. This strategy highlights the rational design of therapeutic metabolites and establishes a new paradigm bridging nanomedicine ...
Kepeng Hu   +17 more
wiley   +1 more source

From Forensics to Forensic Science [PDF]

open access: yesCurrent Issues in Criminal Justice, 2012
The dominant conception of forensic science as a patchwork of disciplines primarily assisting the criminal justice system (defined as ‘forensics’ in this article) is in crisis, or at least shows a ...
Roux, Claude   +2 more
openaire   +2 more sources

Palatable‐Food–Driven Top‐Down Circuit Inhibits PVNCRF Activity to Mitigate Stress Via Peri‐PVNCRFR1 Neurons

open access: yesAdvanced Science, EarlyView.
Palatable food alleviates stress and prevents anxiety. This study uncovers a dedicated neural pathway: dopamine release in the PFC activates D1R neurons, whose projections to the peri‐PVN engage a population of anxiolytic CRFR1 neurons. These neurons then inhibit stress‐induced hyperactivity of PVNCRF neurons, providing a circuit‐level explanation for ...
Yuchuan Hong   +12 more
wiley   +1 more source

Comparative Analysis between Linear Measures from Bidimensional and Three-dimensional Images of the Face for Human Identification Purpose: A Pilot Study

open access: yesJournal of Orofacial Sciences, 2021
Introduction: Photo-anthropometry is a method of facial image comparison that consists of taking measurements on images. The objective of this study was to verify if facial measurements obtained from a two-dimensional (2D) image can be applied for the ...
Paulo H.V Pinto   +4 more
doaj   +1 more source

Enhancing Biogenic Formic Acid Production in the Modified OxFA Process by Acetonitrile Addition

open access: yesAdvanced Science, EarlyView.
In this study, the beneficial effect of using acetonitrile as a co‐solvent in the modified OxFA process is shown, outperforming methanol, demonstrating improved reaction kinetics combined with high selectivity for the HPA‐2 (H5PV2Mo10O40) catalyzed oxidation of xylose to FA.
Jan‐Dominik H. Krueger   +7 more
wiley   +1 more source

Enhancing the Scientific Validity of Methodological Support in Forensic Science: An Important International Trend

open access: yesТеория и практика судебной экспертизы, 2017
One of the key requirements of modern-day forensic practice is to enforce the principle of scientific validity of applied methods. Current practices show that the issues of scientific validity of forensic methodologies and methodological validation of ...
Svetlana A. Smirnova, Aleksandr I. Usov
doaj   +1 more source

Introduction to Forensic Science [PDF]

open access: yesAmerican Society for Clinical Laboratory Science, 2012
1. Donald C. Lehman, EdD, MT(ASCP), SM(NRM)[⇑][1] 1. University of Delaware, Newark, DE 19716 1. Address for Correspondence: Donald C. Lehman, EdD, MT(ASCP), SM(NRM), Department of Med-ical Technology. University of Delaware, Newark, DE 19716, (302) 831-8432, dlehman{at}udel.edu 1. Discuss the role of forensic scientists. 2.
openaire   +2 more sources

Forensic Medicine and Sciences in Turkey

open access: yes, 2015
This chapter provides readers with a better understanding of Turkish Forensic Sciences and the Turkish Legal Medicine and Judicial System as well as its expertise and development.
Gulmen M.K., Ince C.H.
core   +1 more source

Conformational Snapshots of CydDC in a Native Lipid Bilayer Coupling Heme Transport to Antibiotic Resistance

open access: yesAdvanced Science, EarlyView.
Phylogenetic and biochemical analyses of the heme transporter CydDC reveal its functional conservation throughout bacterial evolution and demonstrate its unique asymmetric allosteric mechanism. Furthermore, impairment of CydDC function directly affects bacterial antibiotic resistance and likely compromises antibiotic efficacy through drug efflux.
Lili Yang   +19 more
wiley   +1 more source

Measuring Uncertainty in Forensic Science

open access: yesIEEE Instrumentation & Measurement Magazine, 2021
This paper aims at describing the ways in which uncertainty is (or is not) measured in the field of forensic science and how the measure of uncertainty can be used to make better judicial decisions. From the traditional fingerprint comparison to the latest advances in forensic DNA analysis, we discuss the advantages and drawbacks of various ways of ...
Vuille, Joelle, Taroni, Franco
openaire   +2 more sources

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