Results 81 to 90 of about 4,099,134 (392)

Impact of training in forensic sciences [PDF]

, 2016
INTRODUÇÃO A violência e o trauma subsequente, constituem na atualidade um grave problema de saúde pública em todo o mundo, donde emerge a necessidade dos profissionais que os assistem possuírem conhecimentos atualizados de suporte às boas práticas ...
Coelho, Mauro, Cunha, Madalena, Libório, Rui   +2 more
core  

KRAS/ABHD17C/ALOX15B Axis Promotes Pancreatic Cancer Progression via Ferroptosis Evasion

Advanced Science, EarlyView.
Phosphorylation of ABHD17C induced by KRASmut/ERK signaling facilitates ALOX15B depalmitoylation and degradation via the CUL4/DDB1/DCAF10 complex, thereby enabling KRASmut‐PDAC cell to evade ferroptosis. Methyl protodioscin inhibits KRASmut‐PDAC progression by disrupting the ABHD17C/ALOX15B interaction and inducing ferroptosis, which represents a ...
Man Li, Xuexin Yu, Yuanji Liu, Shuqin Ouyang, Long Wu, Xiaohong Chen, Huiqi Yu, Haoming Chen, Senmao Lian, Ziwen Li, Liyun Gong, Libing Song, Jun Li   +12 more
wiley   +1 more source

An overview of DNA degradation and its implications in forensic caseworks

Egyptian Journal of Forensic Sciences
DNA (deoxy-ribonucleic acid) is a fundamental molecule housing genetic information crucial for forensic casework. However, its integrity is compromised over time due to degradation, affecting living and deceased organisms.
Lina Bhoyar, Palash Mehar, K. Chavali
semanticscholar   +1 more source

The suitability of visual taphonomic methods for digital photographs: An experimental approach with pig carcasses in a tropical climate [PDF]

, 2018
In the context of increased scrutiny of the methods in forensic sciences, it is essential to ensure that the approaches used in forensic taphonomy to measure decomposition and estimate the postmortem interval are underpinned by robust evidence-based data.
Carter, DO, Morgan, RM, Rando, C, Ribéreau-Gayon, A   +3 more
core  

Invalid Forensic Science Testimony and Wrongful Convictions [PDF]

, 2009
This is the first study to explore the forensic science testimony by prosecution experts in the trials of innocent persons, all convicted of serious crimes, who were later exonerated by post-conviction DNA testing.
Garrett, Brandon L., Neufeld, Peter J.
core   +2 more sources

Adaptive Machine Learning for Electronic Nose‐Based Forensic VOC Classification

Advanced Science, EarlyView.
A 32‐element electronic nose enhanced with machine learning demonstrates exceptional accuracy in differentiating between living and deceased individuals (98.1%), discriminating human and animal specimens (97.2%), and estimating postmortem intervals.
Ivan Shtepliuk, Kerstin Montelius, Jens Eriksson, Donatella Puglisi   +3 more
wiley   +1 more source

SIRT6 Lysine‐Demyristoylates ATF2 to Ameliorate Vascular Injury via PRKCD/VE‐Cadherin Pathway Regulating Vascular Endothelial Barrier

Advanced Science, EarlyView.
A novel modified SIRT6 variant (dSIRT6) H133Y‐mediated enrichment technique unmasks 15 new human lysine‐myristoylated proteins. Notably, Sirtuin 6 (SIRT6) demyristoylation of activating transcription factor 2 (ATF2) at K296 orchestrates its nucleoplasmic translocation.
Runyang Feng, Zheyan Fang, Shuang Zhao, You‐en Zhang, Na Wu, Zhenyang Guo, Xin Zhong, Bixuan Jiang, Hongfei Xu, Hangnan Hong, Zhentao Zhang, Mukaddas Abdurahman, Xueting Yu, Jilong Geng, Xiansu Nie, Supuya Abuduwahapi, Dong Huang, Gang Zhao, Wenbin Zhang, Hao Lu, Li Shen, Xin Zhao, Zhaoyang Chen, Junjie Guo, Hongchao Zheng, Yue He, Sanwu Wu, Jiayin Peng, Jiawen Song, Xiao Wang, Haomin Li, Yuli Huang, Shengying Qin, Haojie Lu, Xiangdong Wang, Jianguo Zhao, Lei Huang, Yun Zhao, Peng Li, Junbo Ge, Hua Li   +40 more
wiley   +1 more source

Optimizing Collection of Trace Biological Samples from Vehicle Headrests [PDF]

, 2017
Tape-lifting and swabbing are two methods commonly used for collecting biological samples in the United Kingdom and United States to investigate vehicle crimes.
Bond, John, DeLaTorre, Yvette, Fitch, Ian, Lee, Steven, Ramirez, Jesse, Tang, Kevin, Weart, Jocelyn   +6 more
core   +1 more source

Targeting ROCK2 to Restore Epileptic Synaptic Networks via Mitophagy Activation: Insights from Translational Imaging of SV2A In Vivo

Advanced Science, EarlyView.
By integrating synaptic vesicle glycoprotein 2A PET imaging and transcriptomics, this study identifies Rho‐associated protein kinase 2 (ROCK2) as a critical regulator of synaptic network dysfunction in temporal lobe epilepsy. Pharmacological ROCK2 inhibition restores synaptic density and enhances mitophagy, thereby reducing seizures and neuronal damage.
Ling Xiao, Jing Wang, Bei Chen, Jinhui Yang, Fangyu Wu, Chunyao Zhou, Yifei Zhang, Zhiquan Yang, Dingyang Liu, Lei Tian, Jianhua Yu, Fei Han, Yongxiang Tang, Li Feng, Shuo Hu   +14 more
wiley   +1 more source

Letter to the Editor—Moving Beyond a Lost Cause: Forensic Anthropology and Ancestry Estimates in the United States

Journal of Forensic Sciences, 2020
Editor, Historians of the 21st century will examine the year 2020 and the confluence of seismic events which impacted everyday life in the United States and served to highlight systemic inequalities that have permeated the nation for centuries.
Jonathan D. Bethard, E. DiGangi
semanticscholar   +1 more source