Impact of cardiac and respiratory arrest on cardiac muscle tissue. Wistar rats were injected (on the left) either with cisatracurium to induce a respiratory arrest or lidocaine to induce a cardiac arrest (in the middle). Further, the pathophysiological changes developed and were assessed with linear polarization microscopy at 600–3000 nm wavelength ...
Gennadii Piavchenko +12 more
wiley +1 more source
First multifaceted ADME profile of ACP-105 (CAS: 1048998-11-3): a novel non-steroidal selective androgen receptor modulator used as doping in sports-integrative in silico toxicological studies for clinical and forensic toxicology purposes. [PDF]
Fijałkowska O, Jurowski K.
europepmc +1 more source
Chlorfenapyr reduces testicular weight, sperm quality, and reproductive hormones. This study highlights that RA within chitosan nanoparticles (RA‐CHNPs) are superior to Rosmarinic acid in mitigating CFP‐induced testicular damage. RA within chitosan nanoparticles leads to the reduction of NF‐κB and NLRP3 expression in seminiferous tubules and activates ...
Ahmad Najem Alshammari +6 more
wiley +1 more source
Application of a molecular networking approach using LC-HRMS combined with the MetWork webserver for clinical and forensic toxicology. [PDF]
Magny R +3 more
europepmc +1 more source
A novel synthetic method for three phase I o‐desmethyl NBOMe metabolites bromo‐ (3a) and iodo‐ (13b) and chloro‐ analogue (13c) was developed. LC‐QToF analysis confirmed that the synthetic standards matched the major peaks observed in urine sample screens for each of the respective halogen‐substituted metabolites indicating that the synthesised ...
Jordan Spangler +2 more
wiley +1 more source
Paraquat Poisoning: Insights from Autopsy, Histology, and Liquid Chromatography with Tandem Mass Spectrometry in Multidisciplinary Forensic Toxicology Practice. [PDF]
Nuwongsa I +6 more
europepmc +1 more source
Blood Alcohol Concentration in Finnish Suicide Deaths and Associated Risk Factors, 2016–2024
ABSTRACT Aims There is limited research examining the relationship between blood alcohol concentration (BAC) and other risk factors among suicide deaths in Finland. Our study aimed to investigate the relationship of an elevated (more than zero) blood alcohol concentration with medical history, including sociodemographic characteristics and disease ...
Tristan Pokornyi +2 more
wiley +1 more source
Abstract Background and aims Nitazenes are a novel subclass of synthetic opioids that have been increasingly implicated in the United States (US) overdose crisis. Despite their growing presence in the illicit drug supply, national trends have not been systematically evaluated.
David T. Zhu +3 more
wiley +1 more source
Special issues in forensic toxicology in the Middle East and North Africa (MENA) region: The importance of toxicology amid MENA drug challenges. [PDF]
Al-Asmari AI, Alasmari F, Alsanea S.
europepmc +1 more source
Abstract Background and Purpose New synthetic cannabinoid receptor agonists (SCRAs) are associated with severe adverse effects, including unexpected psychiatric symptoms. These compounds are mainly active through their potent agonism on the cannabinoid receptors CB1 and CB2.
Giorgia Corli +8 more
wiley +1 more source

