Results 91 to 100 of about 12,501 (263)
Investigations Into the Metabolism and Elimination of Tesofensine in Human Urine
Drug Testing and Analysis, EarlyView.This study investigated tesofensine metabolism and urinary elimination after a single 483 μg intake via a dietary supplement. In six volunteers, urine was collected up to 659 h. LC‐HRMS/MS identified four tentative metabolites; maximum urinary concentrations reached 4 ng/mL within 4–48 h.
O. Krug, A. Thomas, M. Thevis
wiley +1 more source
Drug Testing and Analysis, EarlyView.An ultrasensitive LC‐MS/MS method for detecting testosterone esters (T‐esters) in urine at sub–pg/mL levels is presented. This approach, employing Girard P derivatization, provides the first evidence of T‐esters' trace‐level detectability in human urine.
Daniel Pecher +3 more
wiley +1 more source
Drug Testing and Analysis, EarlyView.Box and whiskers plots show the distributions of serum testosterone (T), dihydrotestosterone (DHT), androstenedione (A4), and the ratios of T/FDHT and T/A4. ABSTRACT Detection of androgen doping relies on mass spectrometry‐based methods to detect natural endogenous and exogenous androgens in urine and serum. To distinguish exogenous administration from
D. J. Handelsman, S. Bermon
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Drug Testing and Analysis, EarlyView.First Australian study combining wastewater‐based epidemiology and drug checking, demonstrating how complementary data sources enhance monitoring of illicit drugs and emerging psychoactive substances during high‐use periods. ABSTRACT Consumption of psychotropic drugs is a major economic and public health challenge in Australia.
Muhammad Usman +8 more
wiley +1 more source
Drug Testing and Analysis, EarlyView.Micro‐QuEChERS sample preparation coupled to LC‐QQQ‐MS enabled sensitive quantification of nitazene analogs in 100 μL of plasma. The validated method provided low detection limits and was successfully applied to an authentic intoxication case involving N‐pyrrolidino protonitazene, supporting clinical and forensic toxicology workflows.
Karla A. O. Souza +7 more
wiley +1 more source
Blockchain enhanced smart healthcare management for chronic diseases
Discover ComputingChronic diseases affect millions of people worldwide, making it a significant issue for the efficient and secure management of patient data. Most traditional chronic disease management systems fail to manage data in real time and struggle with ...
Shruti Saxena +3 more
doaj +1 more source
Drug Testing and Analysis, EarlyView.A validated LC‐HRMS/MS method enabled the first quantitative determination of the LGD‐4033 long‐term metabolite (M5‐b) in urine following controlled micro‐dose administration. The generated urinary reference data support the interpretation of adverse analytical findings and anti‐doping result management. ABSTRACT Selective androgen receptor modulators (
Panagiotis Sakellariou +7 more
wiley +1 more source
Adverse childhood experiences, emotion regulation and subjective happiness among young adults
Discover Public HealthAdverse childhood experiences (ACEs) are known to have lasting effects on well-being. This research studies ACEs, subjective happiness, and emotion regulation in young adults.
Pragya Asawa +2 more
doaj +1 more source
Modeling and Output Optimization of Triboelectric Microphone for Acoustic Energy Harvesting
ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.This work elucidates the fundamental multiphysics coupling mechanisms governing acoustic T‐phone, providing a critical theoretical foundation and a predictive design paradigm for the future engineering and deployment of next‐generation, self‐powered acoustic sensors.
Dan Liu +6 more
wiley +1 more source