Evidence for a nuclear compartment of transcription and splicing located at chromosome domain boundaries [PDF]
, 1993 The nuclear topography of splicing snRNPs, mRNA transcripts and chromosome domains in various mammalian cell types are described. The visualization of splicing snRNPs, defined by the Sm antigen, and coiled bodies, revealed distinctly different ...
A Monneron +64 more
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Human Pathology: Case Reports, 2017 Balanitis xerotica obliterans is a chronic dermatosis that frequently involves the glans penis and the foreskin. Granular cell tumor is a benign tumor that may rarely involve the penis, but involvement of the foreskin is exceedingly rare.
Shaun AC Medlicott, MD, FRCPC +1 more
doaj +1 more source
Comparative global immune-related gene profiling of somatic cells, human pluripotent stem cells and their derivatives: implication for human lymphocyte proliferation. [PDF]
, 2017 Human pluripotent stem cells (hPSCs), including embryonic stem cells (ESCs) and induced PSCs (iPSCs), represent potentially unlimited cell sources for clinical applications. Previous studies have suggested that hPSCs may benefit from immune privilege and
Allard, Patrick +12 more
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Redundant prepuce increases the odds of chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS)
Asian Journal of Andrology, 2014 Some published evidence has revealed that the dendritic cells can interact with pathogens that exist in the inner foreskin. This information provides a new vision that pathogens could play a role through the redundant prepuce; numerous studies have ...
Yu-Yang Zhao +6 more
doaj +1 more source
Christians’ Cut: Popular Religion and the Global Health Campaign for Medical Male Circumcision in Swaziland [PDF]
, 2017 Swaziland faces one of the worst HIV epidemics in the world and is a site for the current global health campaign in sub-Saharan Africa to medically circumcise the majority of the male population.
Golomski, Casey, Nyawo, Sonene
core +2 more sources
Frontiers in Immunology, 2022 Whilst short-term oral pre-exposure prophylaxis (PrEP) with antiretroviral drugs in men who have sex with men has shown protection against HIV-1 infection, the impact of this regimen on the in vivo foreskin transcriptome is unknown. We collected foreskin
Stefan Petkov +25 more
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Foreskin care in childhood [PDF]
Canadian Medical Association Journal, 2019 Knowledge of foreskin care is important for both practitioners and parents. Physiologic phimosis (nonretractable foreskin) is normal in childhood. At birth, the inner foreskin is fused to the glans penis; this is termed “physiologic” and rarely requires treatment.
Ryan, McLarty, Darcie, Kiddoo
openaire +2 more sources
Allogeneic human dermal fibroblasts are viable in peripheral blood mononuclear co-culture [PDF]
Universa Medicina, 2014 Background Transplanted allogeneic dermal fibroblasts retain stem cell subpopulations, and are easily isolated, expanded and stored using standard techniques. Their potential for regenerative therapy of chronic wounds should be evaluated.
Restu Syamsul Hadi +2 more
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Phimosis-paraphimosis, is it necessary to operate in emergency?. [PDF]
Batna Journal of Medical Sciences, 2023 The normal foreskin is generally non-retractable due to physiological adhesion between the glans and the inner surface of the foreskin. Phimosis can be primary without signs of scarring, or secondary (pathological) to scarring as balanitis xerotica ...
Hammou Benslimane
doaj +1 more source
Activation of MAPK signalling results in resistance to saracatinib (AZD0530) in ovarian cancer [PDF]
, 2017 SRC tyrosine kinase is frequently overexpressed and activated in late-stage, poor prognosis ovarian tumours, and preclinical studies have supported the use of targeted SRC inhibitors in the treatment of this disease.
El-Helali, Aya +6 more
core +2 more sources