Results 171 to 180 of about 396,384 (287)

Analysing Institutional Set-up of Forest Management in Pakistan [PDF]

open access: yes
This study analyses the institutional set-up of forest management in Pakistan, focusing on the North West Frontier Province, which houses 40 percent of the total forestlands. These areas have faced significant deforestation in the past. It is feared that
Hasan, Lubna
core   +1 more source

Phosphatidic Acid‐TRIM59‐Olig2 Signaling Couples Metabolic Dysfunction to Myelination Failure in PWMI

open access: yesAdvanced Science, EarlyView.
PA accumulates after hypoxic‐ischemic injury and stabilizes the E3 ligase TRIM59 in OPCs. Stabilized TRIM59 enhances ubiquitination and degradation of Olig2, blocking differentiation and causing hypomyelination in PWMI. Modulating PA synthesis restores Olig2 levels, improves myelination, and ameliorates behavioral deficits, defining a metabolically ...
Xinyu Li   +8 more
wiley   +1 more source

“More” Artificial mRNAs: Beyond the Art of Nature

open access: yesAdvanced Science, EarlyView.
Inspired by nature yet transcending it, synthetic mRNA is being redesigned beyond the canonical architecture. This review highlights emerging forms—circular, branched, and self‐amplifying mRNAs—that expand stability, persistence, and functional control, illustrating how artificial mRNA is evolving into a new medium for programmable biological ...
Yuanzhe Cui   +3 more
wiley   +1 more source

Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu   +4 more
wiley   +1 more source

Beyond proxies: towards ecophysiological indicators of drought resistance for forest management. [PDF]

open access: yesTree Physiol
Copie A   +13 more
europepmc   +1 more source

Modelling the impact of forest management and CO2-fertilisation on growth and demography in a Sitka spruce plantation. [PDF]

open access: yesSci Rep, 2023
Argles APK   +14 more
europepmc   +1 more source

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