Results 41 to 50 of about 84,609 (261)

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers, Yaqiao Wei, Dinesh K. Deelchand, Adam Berrington, Young Woo Park, Guita Banan, Michal Povazan, Jens T. Rosenberg, André J. W. van der Kouwe, Tetsuo Ashizawa, Khalaf O. Bushara, Chiadi U. Onyike, Sub H. Subramony, Jeremy D. Schmahmann, Brian J. Soher, Peter B. Barker, Thomas H. Mareci, Eva‐Maria Ratai, Lynn E. Eberly, Gülin Öz   +19 more
wiley   +1 more source

An index for the assessment of degraded Mediterranean forest ecosystems

Forest Systems, 2015
Aim of study: Diagnosing the degradation degree of forest ecosystems is the basis for restoration strategies. However, there is no literature documenting how to quantify the forest degradation degree by using synthetic indicators, also because there is ...
Giuseppe Modica, Angelo Merlino, Francesco Solano, Roberto Mercurio   +3 more
doaj   +1 more source

Does Long‐Term Lower Extremity Strength Training in Adults With Knee Osteoarthritis and Varus Alignment Reduce Knee Joint Loading During Gait?

Arthritis Care &Research, EarlyView.
Objective We examined whether 18 months of strength training in individuals with knee varus alignment and medial tibiofemoral osteoarthritis (OA) reduced knee joint loads during walking compared to an attention control group. Methods This study was a secondary analysis of a randomized clinical trial that compared the effects of strength training to a ...
Stephen P. Messier, Matthew N. Vigliotti, Paige E. Rice, Brian Pietrosimone, Shannon L. Mihalko, Edward H. Ip, Richard F. Loeser, David J. Hunter, Ali Guermazi, Ryan Hill, Santiago Saldana, Kim L. Bennell, Paul DeVita   +12 more
wiley   +1 more source

Remote sensing of forest degradation in Southeast Asia—Aiming for a regional view through 5–30 m satellite data

Global Ecology and Conservation, 2014
In this review paper we present geographical, ecological and historical aspects of Southeast Asia from the perspective of forest degradation monitoring and critically discuss available approaches for large area forest degradation monitoring with ...
Jukka Miettinen, Hans-Jürgen Stibig, Frédéric Achard   +2 more
doaj   +1 more source

A Low-Cost and Robust Landsat-Based Approach to Study Forest Degradation and Carbon Emissions from Selective Logging in the Venezuelan Amazon

Remote Sensing, 2021
Selective logging in the tropics is a major driver of forest degradation by altering forest structure and function, including significant losses of aboveground carbon.
Carlos Pacheco-Angulo, Wenseslao Plata-Rocha, Julio Serrano, Emilio Vilanova, Sergio Monjardin-Armenta, Alvaro González, Cristopher Camargo   +6 more
doaj   +1 more source

Zein‐Based Adhesives: Sustainable Extraction and Application in Bioadhesive Technologies

Advanced Engineering Materials, EarlyView.
Zein is extracted from corn gluten meal using a simple and scalable process with high yield (~90%). The resulting protein is applied in bioadhesives modified with Ca2+ and Fe3+ ions, exhibiting substrate‐dependent adhesion. The findings demonstrate competitive bonding performance and highlight the role of ionic interactions in tuning adhesion ...
Paula Bertolino Sanvezzo, Daniela Winsley Valereto Friozi, Vinícius de Oliveira, Marcia Cristina Branciforti   +3 more
wiley   +1 more source

Forest Management Regimes and Drivers of Forest Cover Loss in Forest Reserves in the High Forest Zone of Ghana

International Journal of Forestry Research, 2020
Forest cover loss, particularly those arising from deforestation and forest degradation, is largely driven by human activities and has attracted global attention over the decades. Globally, countries have adopted strategies to manage and conserve forests
Frank Ankomah, Boateng Kyereh, Michael Ansong, Winston Asante   +3 more
doaj   +1 more source

Characterizing Forest Change Using Community-Based Monitoring Data and Landsat Time Series. [PDF]

PLoS ONE, 2016
Increasing awareness of the issue of deforestation and degradation in the tropics has resulted in efforts to monitor forest resources in tropical countries.
Ben DeVries, Arun Kumar Pratihast, Jan Verbesselt, Lammert Kooistra, Martin Herold   +4 more
doaj   +1 more source

Current Status and Challenges in Data Collection for Aerospace Coatings Deposited by Plasma Spraying

Advanced Engineering Materials, EarlyView.
An innovative approach has been integrated into the GRENAT project to optimize plasma spraying and coating performance. Raw materials are accelerated and melted in the plasma generated by torches, creating coatings. Monitoring sensors collect process data which are combined with ex situ characterization data.
Lila Randriamananjara, Vincent Rat, Quentin Dubreuil, Patrice Valorge, Simon Goutier, Alain Denoirjean, Olivier Messe, Céline Ruelle, Jean‐Philippe Poli   +8 more
wiley   +1 more source