Results 161 to 170 of about 146,648 (263)

Targeting WDR12 Unleashes T‐Cell‐Mediated Antitumor Activity in Melanoma by Destabilizing CD276

Advanced Science, EarlyView.
WDR12 cooperates with the chaperonin subunit CCT7 to maintain CD276 stability on tumor cells, suppressing T‐cell activity and promoting immune escape. SU14813, a small‐molecule WDR12 inhibitor, reduces CD276 stability and relieves CD276‐mediated T‐cell suppression.
Jie Pan, Ruimin Chang, Meng Zhang, Qian Dong, Guanxiong Zhang, Xiang Chen, Mingliang Chen, Lixia Lu, Xiaowei Liang, Yeye Guo, Juan Su   +10 more
wiley   +1 more source

Increase in wild animal consumption across Central Africa. [PDF]

Nature
Bessone M, Ingram DJ, Abernethy K, Abua S, Allebone-Webb S, Antonacci D, Kim R, Brittain S, Cornelis D, Detoeuf D, Emogor CA, Fa JE, Fa JE, Foerster S, Fonteyn D, Grande Vega M, Hodgkinson C, Ickowitz A, Kamogne Tagne CT, Kemalasari D, Kümpel N, Lhoest S, Mavah G, Mouanda Niamba RG, Iponga DM, Milner-Gulland EJ, Muhindo J, Munyuli T, Nasi R, Ngama S, Nyumu J, Ombeni J, Poulsen JR, Rowland D, Sampurna Y, Sandrin F, Starkey M, Tata C, Tieguhong JC, van Vliet N, Vigneron P, Whytock RC, Wieland M, Wilkie D, Willis J, Wright J, Coad L.   +46 more
europepmc   +1 more source

Advancing the Design of High‐Efficiency Printable Hole‐Conductor‐Free Mesoscopic Perovskite Solar Cells Through Machine Learning

Advanced Science, EarlyView.
Based on the largest printable mesoscopic perovskite solar cells database we established, stacking model achieved precise PCE prediction (R2 = 0.73, MAE = 2.18%). Multiple experiments verified the accuracy of the model, which guided the fabrication of high‐PCE devices with an efficiency of 19.36%.
Hao Meng, Jingzi Zhang, Xu Zhu, Yuelin Wang, Antai Yang, Kailong Hu, Chengquan Zhong, Jiakai Liu, Menghan Dun, Xi Lin   +9 more
wiley   +1 more source

Using Metabarcoding Techniques to Map Multiple Dung Beetle-Vertebrate iDNA Networks in a Southeast Asian Forest. [PDF]

Mol Ecol Resour
Ong XR, Drinkwater R, Cheong SKS, Loh RK, Kim HL, Dos Santos AL, Puniamoorthy N, Slade EM.   +7 more
europepmc   +1 more source

Ovarian Cancer Diagnosis and Chemoresistance Prediction Model Based on cfRNA Molecular Signature

Advanced Science, EarlyView.
A deep learning model analyzes cfRNA profiles extracted from the blood of OVCA patients. This innovative approach distinguishes OVCA from healthy controls with high accuracy. Crucially, it reliably predicts patient response to chemotherapy (sensitive versus resistant subgroups).
Qinhao Guo, Yangyang Zhang, Yongcheng Jin, Siwei Deng, Yongqi Chen, Zheng Feng, Hao Wen, Liu Wang, Yilin Li, Fanghong Ou, Yong Shen, Haiming Li, Tianyao Zhou, Xingzhu Ju, Xiaohua Wu   +14 more
wiley   +1 more source

Efficacy of Cognitive Behavioral Therapy Combined with Exercise in Patients with Chronic Pain: A Systematic Review and Meta-Analysis. [PDF]

J Pain Res
Zhang YZ, Yang B, Jiang CH, Guo YX, Lai XX, Zhang WQ, Zhang H.   +6 more
europepmc   +1 more source

Forest environmental education

The Japanese Forest Society Congress, 2007
openaire   +1 more source

Non‐Noble Metal Nanocatalysts for Hydrogen Evolution

Advanced Science, EarlyView.
Recent overviews and latest developments of diverse classes of non‐noble catalysts for application toward high‐performance photocatalysis, thermocatalytic steam reforming, and electrocatalysis. Toward sustainability objectives, several advanced characterization tools in combination with the latest breakthroughs in machine learning for material ...
Lina Jaya Diguna, Gede Herry Arum Wijaya, Md Abdul Kuddus Sheikh, Tobias Haposan, Fidelis Stefanus Hubertson Simanjuntak, Arramel Arramel, Muhammad Danang Birowosuto, Konstantin Sergeevich Novoselov   +7 more
wiley   +1 more source

Palmitoylation of PSD‐95 Orchestrates Learning‐Dependent Metaplasticity in the Amygdala and Fear Memory

Advanced Science, EarlyView.
This study reveals that fear learning specifically triggers PICK1/DHHC2‐dependent palmitoylation of PSD‐95 in the lateral amygdala. Fear conditioning induces the dissociation of DHHC5 from PSD‐95 and the association of PSD‐95 with DHHC2. DHHC2‐mediated palmitoylation of PSD‐95 is required for synaptic transmission and underlies fear learning–induced ...
Zu‐Cheng Shen, Yu‐Xuan Weng, Zhi‐Xuan Xia, Yue‐Ling Zhao, Qian‐Qian Ding, Si‐Ying Wang, Ting Cao, Xuan‐Ying Chen, Wu‐Cheng Tao, Shen Lin, Zhou Chen, Yi‐Xiao Luo   +11 more
wiley   +1 more source

The effectiveness of school-based physical activity interventions on health-related fitness and BMI in South Korea: a three-level meta-analysis. [PDF]

Front Pediatr
Song J, Choi W.
europepmc   +1 more source