Results 231 to 240 of about 682,749 (278)

Engineered GM1 Intersects Between Mitochondrial and Synaptic Pathways to Ameliorate ALS Pathology

Advanced Science, EarlyView.
Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease driven by genetic and molecular disruptions affecting energy balance, protein homeostasis, and stress responses in nerve cells. Studies using human and rodent models identified convergent defects in mitochondria and synaptic function.
Federica Pilotto, Tristan Dellazizzo Toth, Silvano Bond, Alexander Schmitz, Rim Diab, Sara Y. Ngo Tenlep, Brian Mooney, Silvia Erni, Martina Schobesberger, Olivier Scheidegger, Camille Peitsch, Smita Saxena   +11 more
wiley   +1 more source

A General Surrogate Model for CO₂ Flooding Dynamic Prediction Based on Dimensionless Features and Implicit Time. [PDF]

ACS Omega
Li C, Wang X, Yu W, Zhou P.
europepmc   +1 more source

On pruning and feature engineering in Random Forests

, 2016
Khaled Fawagreh
openalex   +1 more source

Endogenous “Time Bomb” – Mislocalized Phospholipase A2 as a Critical Mediator of Ultra‐Rapid Mortality in Sepsis and Acute Lung Injury

Advanced Science, EarlyView.
Phospholipase A2 (PLA2), a dormant enzyme, becomes lethal when activated—collapsing lungs in minutes. Our dual therapy (DOPS + varespladib) boosts survival from 0% to >90% in sepsis/ALI. A breakthrough for acute lung injury treatment. ABSTRACT This study reveals that phospholipase A2 (PLA2), normally stable and nontoxic, can be activated specifically ...
Jianyu Wang, Zhongxing Xu, Lin Wang, Xin Sui, Yuan Luo, Xiuli Zhao, Jun Yang, Yongan Wang   +7 more
wiley   +1 more source

From Correlation to Causation: A Petrophysics-Informed Framework for Optimizing Hydraulic Fracturing in Tight Gas Reservoirs. [PDF]

ACS Omega
Guo Y, Li Z, Yang F, Huang X.
europepmc   +1 more source

Faculty of Forestry, University of Zagreb and Department of Forest Engineering in the Bologna Process

, 2007
A. P. B. Krpan
openalex   +1 more source

On the Origins of Toughness in Corymbia calophylla (Marri Tree) Nuts

Advanced Science, EarlyView.
We uncover the natural toughening mechanisms of the marri nut, including fiber pullout, crack deflection, and a viscoelastic matrix, which enable exceptional energy absorption and ductility comparable to Teflon, with an elastic modulus similar to acrylic.
Wegood M. Awad, Ahmed S. Dalaq, Marieh B. Al‐Handawi, Rezo Getsadze, Oraib Al‐Ketan, James Weston, Mohammed Daqaq, Panče Naumov   +7 more
wiley   +1 more source

Flight delay prediction: Evaluating machine learning algorithms for enhanced accuracy. [PDF]

PLoS One
AlBassam SAA, AlShahrani DN.
europepmc   +1 more source

Landscape engineering in the national forests

, 1918
openaire   +3 more sources