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An Insulin‐Exosome‐TNFAIP8 Axis Drives Stromal Fibrosis and Therapeutic Resistance in Pancreatic Cancer

open access: yesAdvanced Science, EarlyView.
In pancreatic ductal adenocarcinoma (PDAC), insulin is associated with activation of PI3K/AKT–RAB3A signaling and enhanced secretion of TNFAIP8‐enriched exosomes from tumor cells. Uptake of these exosomes by fibroblasts is linked to TRIM21‐dependent STAT1 degradation and the emergence of myofibroblastic CAF–associated features, accompanied by increased
Zhenyu Li   +15 more
wiley   +1 more source

Intelligent prediction of heat capacity of polyethylene glycol polymer. [PDF]

open access: yesSci Rep
Al-Nabulsi JI   +8 more
europepmc   +1 more source

Lightweight machine learning framework using temporal features for electric vehicle demand response forecasting on edge devices. [PDF]

open access: yesSci Rep
Durrani AM   +8 more
europepmc   +1 more source

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