Results 21 to 30 of about 679,608 (305)

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Enzymatic activities and degradation properties of fungi isolated from decayed Quercus variabilis

Journal of Wood Science
The objective of this study is to investigate the microorganisms responsible for the decay of Quercus variabilis. Fungi were isolated and identified from collected Q.
Hyunjeong Na, Sae-Min Yoon, Sanghoon Chung, Mi-Jin Park   +3 more
doaj   +1 more source

Intermediate Role of Presenteeism in Relationship Between Organizational Stress and Organizational Silence: A Research on Forest Industry Employees

Drvna Industrija, 2023
The purpose of this study is to investigate the mediating role of presenteeism in the relationship between organizational stress and organizational silence of 305 forest products employees in İstanbul and Kocaeli, Turkey.
Nadir Ersen, Ugur Can Usta, Bahadir Cagri Bayram, lker Akyüz   +3 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Drought effects on large fire activity in Canadian and Alaskan forests [PDF]

, 2007
Fire is the dominant disturbance in forest ecosystems across Canada and Alaska, and has important implications for forest ecosystems, terrestrial carbon dioxide emissions and the forestry industry.
Xiao, Jingfeng, Zhuang, Qianlai
core   +2 more sources

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Biodiversity conservation in Southeast Asian timber concessions : a critical evaluation of policy mechanisms and guidelines [PDF]

, 2008
Tropical deforestation is leading to a loss of economically productive timber concessions, as well as areas with important environmental or socio-cultural values.
Dennis, R.A., Gustafsson, Lena, Nasi, Robert   +2 more
core  

The Canadian ‘Model Forest’ approach : a way forward for Tasmania? [PDF]

, 2004
Forest policy and forestry management in Tasmania have undergone a number of changes in the last thirty years, many explicitly aimed at improving industry sustainability, job security, and forest biodiversity conservation.
Gray, Matthew, Wolfenden, John A.J.
core   +2 more sources

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

Reduced-Pressure Boiling Extraction of Oleuropein Coupled with Ultrasonication from Olive Leaves (Olea europaea L.)

Advances in Materials Science and Engineering, 2015
Oleuropein was extracted from Frantoio olive leaves using reduced-pressure boiling extraction coupled with ultrasound-assist (URPE). Four important factors, extraction temperature, ultrasonic power, ethanol concentration, and the ratio of solid to liquid,
Pu-jun Xie, Li-xin Huang, Cai-hong Zhang, Feng You, Cheng-zhang Wang, Hao Zhou   +5 more
doaj   +1 more source