Results 51 to 60 of about 8,461,198 (336)
Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes
FEBS Letters, EarlyView.Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley +1 more source
Molecular Oncology, EarlyView.This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu +12 more
wiley +1 more source
Scientific DataEstimating growing stock is one of the main objectives of forest inventories. It refers to the stem volume of individual trees which is typically derived by models as it cannot be easily measured directly.
Markus Didion +8 more
doaj +1 more source
Into the void: ECM fungal communities involved in the succession from rockroses to oak stands
Scientific Reports, 2023 Oak forests accompanied by Cistus species are a common landscape in the Mediterranean basin. It is argued that Cistus dominated fields serve as recruitment areas for Quercus seedlings, as they help in the transmission of the fungal community through ...
Ignacio Sanz-Benito +7 more
doaj +1 more source
Molecular Oncology, EarlyView.This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh +8 more
wiley +1 more source
Streamflow response to forest management
Nature, 2020 Forests play a key part in the water cycle, so both planting and removing forests can affect streamflow. In a recent Article1, Evaristo and McDonnell used a gradient-boosted-tree model to conclude that streamflow response to forest removal is predominantly controlled by the potential water storage in the landscape, and that removing the world’s forests
James W. Kirchner +6 more
openaire +6 more sources
Molecular Oncology, EarlyView.RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha +10 more
wiley +1 more source
Testing the influence of habituation on genetic structure of brown bear (Ursus arctos)
Annals of Forest Research, 2015 Adult bear individuals live solitary and haveprolonged parent–offspring relationships, therefore the share of learned skills compared to the inherited ones is much larger than in other carnivores.
Ancuţa Cotovelea +9 more
doaj +1 more source
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source