Results 31 to 40 of about 293 (217)

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

Avaliação operacional e econômica do "feller-buncher" em dois subsistemas de colheita de florestas de eucalipto Technical and economic analysis of a feller-buncher in two harvest subsystems of eucalyptus forests

open access: yesRevista Árvore, 2004
O objetivo deste trabalho foi avaliar técnica e economicamente o feller-buncher em dois subsistemas de colheita em florestas de eucalipto. A análise técnica englobou um estudo de tempos e movimentos e de produtividade.
Fábio Murilo Tieghi Moreira   +4 more
doaj   +1 more source

Economic basis and an experience of plantation forest growing in the Central Volga Region [PDF]

open access: yesСибирский лесной журнал, 2018
Conceptual-methodological and economic bases of plantation forest growing are developed. The mathematical models of the dynamics of the productivity of stands of different tree species in the rich types of the forest-growing conditions of the Middle ...
Yu. P. Demakov   +3 more
doaj   +1 more source

Mechanized excavation of fruit and forest seedlings [PDF]

open access: yesSavremena poljoprivredna tehnika, 2019
The paper presents the possibilities of mechanized harvesting of fruit and forest seedlings. For this purpose, special purpose plows with a special working body are most used for undercutting the soil layer and the root system of seedlings with the lifting and shaking of a part of the soil. Older plow solutions for fruit and forest seedlings still used
Rajko Bugarin   +3 more
openaire   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Technical and Economical Evaluations of Maritime Pine Plantations in Western Black Sea Region of Turkey

open access: yesForestist, 2012
In this study, technical and economical evaluations of the maritime pine (Pinus pinaster Aiton.) plantations, established at Bartın-Karaçaydere between the years of 1979 and 1984, were made.
Korhan Tunçtaner   +3 more
doaj   +1 more source

Mining the forest: uncovering biological mechanisms by interpreting Random Forests [PDF]

open access: yes, 2017
Abstract Biological datasets are large and complex. Machine learning models are therefore essential to capture relationships in the data. Unfortunately, the inferred complex models are often difficult to understand and interpretation is limited to a list of features ranked on their importance in the model.
de Ruiter, Julian   +2 more
openaire   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Social promotion of forest workers.

open access: yesSilva Fennica, 1979
Alongside the extent of forest production, the demand for labour input in forestry depends on the development of the structure of production and of the productivity of the work.
Kantola, Mikko
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

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