Results 51 to 60 of about 351,790 (300)

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Current situation of Forest Sciences in UNACIFOR. Perspectives from the competences and extensionism

open access: yesRevista Cubana de Ciencias Forestales, 2022
The major of Forest Sciences, constitutes in The National University of Forestry Sciences (UNACIFOR), of Honduras, an important pillar for its professional profile, for the social commission and the typical characteristics of Honduras as a purely forest ...
José Fidel Alvarado Sánchez   +1 more
doaj  

Towards new agriculture and forest academy

open access: yesSilva Fennica, 1989
This paper is a commentary which summarises the history of the Finnish Society of Forest Science and its connection to the corresponding society in the field of agriculture, the Scientific Agricultural Society of Finland.
Leikola, Matti
doaj   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Climatic factors controlling stem growth of alien tree species at a mesic forest site: a multispecies approach

open access: yes, 2023
The introduction of non-native species with various ecological and functional traits to European forests may be a potential tool for mitigating climate risks.
Hoffmann, Nils; Department of Silviculture and Forest Ecology of the Temperate Zones, Faculty of Forest Sciences and Forest Ecology, University of Göttingen, Göttingen, Germany   +7 more
core   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

Active forest ownership – Perception of Finnish women forest owners [PDF]

open access: yes
“Active forest ownership” is often understood as a masculine and timber production-centric concept. The objective of this article is to study how women forest owners perceive the concept of “active forest ownership”. Twenty-two semi-structured interviews
Hamunen, Katri   +2 more
core   +1 more source

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