Results 171 to 180 of about 1,736,079 (311)

A Unified Hierarchical Multiscale Fusion Framework for Drug–Target Affinity Prediction: From Benchmark Performance to Nanomolar Inhibitor Discovery

Advanced Science, EarlyView.
A multimodal fusion framework integrating sequence, atomic, and fragment representations captures drug–target interactions across multiple scales. The model delivers strong predictive performance and enables efficient virtual screening. Applied to hematopoietic progenitor kinase 1 (HPK1), it identifies structurally diverse inhibitors with nanomolar ...
Shuo Liu, Xiang Zhang, Haixia Feng, Yuquan Li, Xiaoqing Gong, Yong Liang, Xiaojun Yao, Huanxiang Liu   +7 more
wiley   +1 more source

A comparison of twenty-six baits for isolating <i>Calonectria</i> species illustrates differences in their efficacy and relevance. [PDF]

IMA Fungus
Zhou H, Dong H, Zhou W, Wingfield MJ, Chen S.   +4 more
europepmc   +1 more source

Forest Tree Seed Directory [PDF]

Nature, 1962
openaire   +1 more source

Dual pKa Lipid Nanoparticles for Lung‐tropic mRNA Delivery and pH‐Programmed Endosomal Escape

Advanced Science, EarlyView.
Lipid nanoparticles’ bottleneck lies in low endosomal escape efficiency and liver‐dominant delivery after intravenous administration. To overcome these limitations, we present a stepwise pH‐programmed lipid nanoparticle system enabled by our newly synthesized ionizable lipid.
Seong Gi Lim, Minju Lee, Yiming Wang, Eunjin Choi, Ji Sun Park, Kyungmin Park, Hayoung Jeon, Donghyun Kim, Donghyun Lee, Yeeun Lee, Kee‐Pyo Kim, Eunha Kim, Heebeom Koo   +12 more
wiley   +1 more source

Coefficient of variation of normal seedlings obtained from the validation of methods for the seed germination testing of 20 species belonging to the family Fabaceae

Journal of Seed Science
The standardization of inter-laboratory results of germination test of forest species seeds requires that the methods be robust. Therefore, the objective was to compare and discuss, through the coefficient of variation for normal seedlings, the ...
Vanderley José Pereira, Denise Garcia Santana   +1 more
doaj  

Potential of Korean forest tree seed extracts as multifunctional bioresources: Evaluation of Antioxidant, anti-inflammatory, whitening, and anticancer activities. [PDF]

PLoS One
Lee H, Park K, Jang BK, Kwon YR, Cho JS.
europepmc   +1 more source

Leveraging Microphysiological Systems to Facilitate Neutrophil‐Based Cancer Immunotherapy

Advanced Science, EarlyView.
Microphysiological systems are emerging as powerful human‐relevant platforms for studying neutrophil biology in cancer. Current applications of spheroids, organoids, and organ‐on‐a‐chip models are reviewed, together with future opportunities in behaviorome profiling, multi‐omics integration, personalized medicine, immune crosstalk, and multi‐organ ...
Shuai Shao, Markus Isfeld Diehl, Caroline N. Jones   +2 more
wiley   +1 more source

Recovery of Seed Quality and Germination Success Following Severe Wildfires in <i>Araucaria araucana</i> Forests of the Southern Andes. [PDF]

Ecol Evol
Fuentes-Ramírez A, Díaz-Mons B, Vargas-Gaete R, Herrera H, Almonacid L.   +4 more
europepmc   +1 more source

The Wake Forest Review [June 1976]

, 1976
June 1976 issue of The Wake Forest ...

core  

Multifunctional Nanovaccine‐Radiotherapy Synergy Drives Anti‐Tumor Immunity via Multi‐Cascade Cell Death for Pancreatic Cancer Therapy

Advanced Science, EarlyView.
Machine‐learning‐driven transcriptomic analysis identifies FSTL3 as a key tumor‐microenvironment regulator in desmoplastic pancreatic adenocarcinoma. A cRGD‐modified liposome co‐loading gemcitabine and siFSTL3 serves as an irradiation‐triggered in situ nanovaccine. It synergizes with radiotherapy to induce ferroptosis and immunogenic cell death through
Chengyi Huang, Yushu Han, Xiang Liu, Chuanhao Wang, Xiaofei Zhu, Di Chen, Yangyang Gong, Liang Chen, Wenjuan Chen, Zhenyuan Miao, Bufu Tang, Huojun Zhang   +11 more
wiley   +1 more source