Results 31 to 40 of about 238,920 (268)

Admixture Mapping Reveals Candidate Regions for Methotrexate Neurotoxicity Susceptibility: A Reducing Disparities in Acute Leukemia Consortium Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Neurotoxicity is a rare, often dose‐limiting adverse effect of methotrexate (MTX) therapy that disproportionally affects Latino children. Factors contributing to the observed disparity are not well understood. This study leveraged admixture mapping to identify genetic regions associated with MTX‐related neurotoxicity susceptibility ...
Rachel D. Harris   +24 more
wiley   +1 more source

On Hierarchical Composite Endpoints in Pediatric Cancer Supportive Care: Illustrative Examples From Two Multi‐Center Phase‐III Randomized Clinical Trials

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric supportive care clinical trials often involve multiple clinically important outcomes, complicating trial interpretation. Hierarchical composite endpoints (HCEs) provide a framework to integrate key outcomes according to clinical importance.
Willem H. Collier   +11 more
wiley   +1 more source

Features and Partial Derivatives of Bertalanffy-Richards Growth Model in Forestry

open access: yesNonlinear Analysis, 2004
The Bertalanffy-Richards growth model is employed more than any other models for forest growth and yield modelling. However, its features have not completely been recognised.
Y. C. Lei, S. Y. Zhang
doaj   +1 more source

Designing a Validation Protocol for Remote Sensing Based Operational Forest Masks Applications. Comparison of Products Across Europe

open access: yesRemote Sensing, 2020
The spatial and temporal dynamics of the forest cover can be captured using remote sensing data. Forest masks are a valuable tool to monitor forest characteristics, such as biomass, deforestation, health condition and disturbances. This study was carried
Angel Fernandez-Carrillo   +4 more
doaj   +1 more source

Occurrence of Extramedullary Relapses in Pediatric Acute Lymphoblastic Leukemia After Treatment With Blinatumomab

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT We report a retrospective single‐center analysis of pediatric patients with relapsed or refractory B‐cell precursor acute lymphoblastic leukemia focusing on relapses outside of the typical locations, bone marrow, central nervous system, or testes.
Johanna Kunz   +7 more
wiley   +1 more source

Evidence, Perceptions, and Trade-offs Associated with Invasive Alien Plant Control in the Table Mountain National Park, South Africa

open access: yesEcology and Society, 2012
The Table Mountain National Park is a 265 km2 protected area embedded within a city of 3.5 million people. The park contains an extremely diverse flora with many endemic species, and has been granted World Heritage Site status in recognition of this ...
Brian W. van Wilgen
doaj   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

CO2 payback time for a wind farm on afforested peatland in the UK [PDF]

open access: yesMires and Peat, 2010
The siting of wind farms on natural and afforested upland peatlands presents an interesting public policy dilemma. Such locations may offer developers attractive wind characteristics amidst sparse human settlement, but the associated disturbance of ...
J.T. Mitchell, J. Grace, G.P. Harrison
doaj  

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