Principles for Rigorous Design and Application of Synthetic Microbial Communities
SynComs are artificially designed to enable inter‐species metabolic interactions, metabolic division of labor, and ecological interactions that can elicit phenotypes like colonization stability and environmental adaptation. This systematic review explores the processes used to construct SynComs, the assessment of the mechanisms of metabolic interaction
Yuxiao Zhang +21 more
wiley +1 more source
3-dimensional surface geometry, optical properties dataset of Scots pine and Norway spruce shoots. [PDF]
Borysenko O +7 more
europepmc +1 more source
A new cerebrocortical organoid model using isogenic hiPSCs with familial Alzheimer's mutations recapitulates key AD features, including amyloid‐beta and phospho‐Tau aggregation, neuronal hyperexcitability, and synapse loss. Single‐cell RNA‐seq reveals aberrant pathways in excitatory and inhibitory neurons.
Sergio R. Labra +23 more
wiley +1 more source
Impact Mechanism of Spectral Differentiation on PV Performance and Optimization of PV Systems in Shaded Forest Environments. [PDF]
Yang D, He Y, Ga L, Xu D, Bai X, Li W.
europepmc +1 more source
Aberrant Splicing Signatures Underpin Oligodendrocyte Damage in ALS and Neuron Loss in FTD
Integrating bulk and single‐nucleus RNA‐seq from ALS and FTD patients, we revealed distinct cellular dysfunctions, with severe oligodendrocyte damage in ALS and pronounced neuron loss in FTD. We identified cell‐type‐specific aberrant splicing events as potential biomarkers with robust classification performance, some of which produce de novo peptides ...
Chen Du +6 more
wiley +1 more source
Integrating meteorological and breeding data to predict maize yields using machine learning algorithms. [PDF]
Wang S +7 more
europepmc +1 more source
HiFiCCL, as the first assembly framework specifically designed for low‐coverage high‐fidelity reads, improves the assembly quality of existing assemblers and also enhances downstream applications such as large structural variant (SV) detection (>10 000 bp), synteny analysis, pangenome graph construction, and graph‐based individual‐specific germline SVs
Zhongjun Jiang +9 more
wiley +1 more source
Integrated biotechnological and artificial intelligence innovations for plant improvement. [PDF]
Wu H, Luo M, Liu Y, Yang J, Cao Y.
europepmc +1 more source
A Novel 10‐Protein Score for Liver Fat Content Predicts Cardiovascular‐Kidney‐Metabolic Disease Risk
A novel 10‐protein plasma score precisely quantifies liver fat, outperforming the fatty liver index. It robustly predicts the risk of numerous cardiovascular‐kidney‐metabolic diseases and integrates with genetic data for precision prevention, offering a practical alternative to magnetic resonance imaging (MRI). Abstract Liver fat content (LFC) is a key
Xiaoqin Gan +12 more
wiley +1 more source
Trunk Detection in Complex Forest Environments Using a Lightweight YOLOv11-TrunkLight Algorithm. [PDF]
Zhang S +6 more
europepmc +1 more source

