Results 221 to 230 of about 23,633 (272)

The Weak Core, Partition‐Based Universal Stability, and Their Risk Associations Through A Partial Order

open access: yesNaval Research Logistics (NRL), EarlyView.
ABSTRACT We are concerned with the stability of a transferable‐utility cooperative (TU) game. First, the concept of core can be weakened so that the blocking of changes is limited to only those with multilateral backings. This principle of consensual blocking, as well as the traditional core‐defining one of unilateral blocking and one straddling in ...
Jian Yang
wiley   +1 more source

Disarming the Hsp70–Bim Alliance: Small‐Molecule and Peptidic Disruptors of a Chaperone‐Apoptotic Switch in Cancer

open access: yesChemistryOpen, EarlyView.
Targeting a nucleotide‐sensitive groove on Hsp70 that binds the Bim BH3 helix, we integrate structures, biophysics, and SAR from peptides, fragments, and phenalene‐dicarbonitrile “wedges.” These disrupt the Hsp70–Bim complex with sub‐µM cellular engagement and in vivo activity while sparing Hsp90/mortalin.
Emadeldin M. Kamel   +5 more
wiley   +1 more source

Localization Through Coordination? Implementing the Humanitarian‐Development‐Peace Nexus in the Democratic Republic of the Congo

open access: yesPublic Administration and Development, EarlyView.
ABSTRACT As a global concept and initiative, the Humanitarian‐Development‐Peace Nexus (HDPN) aims to improve integration across the traditionally siloed humanitarian, development, and security sectors, while foregrounding the involvement of local actors.
Marie‐Eve Desrosiers   +1 more
wiley   +1 more source

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