Results 101 to 110 of about 34,335,892 (348)

The toxic mechanism and application of tetrodotoxin (TTX) [PDF]

open access: yesMATEC Web of Conferences
Tetrodotoxin (TTX) is a powerful toxin related to nerve cells that is commonly discovered at loads of puffer fish, and working out the best way of cooking, whereas keeping the flavour but getting rid of the toxicity has challenged people for decades ...
Zhang Xiaonan
doaj   +1 more source

Approximating L^2-signatures by their compact analogues

open access: yes, 2001
:Let G be a group together with an descending nested sequence of normal subgroups G=G_0, G_1, G_2 G_3, ... of finite index [G:G_k] such the intersection of the G_k-s is the trivial group.
Lueck, Wolfgang, Schick, Thomas
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Maslov index, Lagrangians, Mapping Class Groups and TQFT

open access: yes, 2011
Given a mapping class f of an oriented surface Sigma and a lagrangian lambda in the first homology of Sigma, we define an integer n_{lambda}(f). We use n_{lambda}(f) (mod 4) to describe a universal central extension of the mapping class group of Sigma as
Birman J.   +4 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Investigation of peri-implant tissue conditions and peri-implant tissue stability in implants placed with simultaneous augmentation procedure: a 3-year retrospective follow-up analysis of a newly developed bone level implant system

open access: yesInternational Journal of Implant Dentistry, 2017
Background Guided bone regeneration (GBR) has been proven to be a reliable therapy to regenerate missing bone in cases of atrophy of the alveolar crest.
Jonas Lorenz   +3 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Calcia magnesia alumino silicate (CMAS) corrosion attack on thermally sprayed thermal barrier coatings: a comprehensive review

open access: yesnpj Materials Degradation
Calcia-Magnesia-Alumino Silicate (CMAS) is a form of molten siliceous residue generated at elevated temperatures within aeroengines. CMAS adheres to the surface of thermal barrier coatings (TBCs) and has the potential to cause significant damage to ...
Rakesh Bhaskaran Nair, Dermot Brabazon
doaj   +1 more source

Three Milliliters of Peripheral Blood Is Sufficient for Preparing Liquid Platelet-Rich Fibrin (PRF): An In Vitro Study

open access: yesBioengineering
Platelet-rich fibrin (PRF) has assumed an important role in supporting tissue regeneration in different fields. To date, the standard protocol for liquid PRF requires at least 10 mL of peripheral blood. The present study aimed to analyze the composition,
Sarah Al-Maawi   +3 more
doaj   +1 more source

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