Results 141 to 150 of about 3,197,212 (313)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Proposal of Difference-Frequency Wave Generation Induced by Dual-Wavelength Free-Electron Laser Oscillations

Photonics
Optical klystrons have been developed in storage ring free-electron lasers (FELs) as insertion devices to increase the FEL gain in a straight section with limited length.
Norihiro Sei, Takeshi Sakai, Heishun Zen, Hideaki Ohgaki   +3 more
doaj   +1 more source

Measurement of the axial vector form factor from antineutrino-proton scattering. [PDF]

Nature, 2023
Cai T, Moore ML, Olivier A, Akhter S, Dar ZA, Ansari V, Ascencio MV, Bashyal A, Bercellie A, Betancourt M, Bodek A, Bonilla JL, Bravar A, Budd H, Caceres G, Carneiro MF, Díaz GA, da Motta H, Felix J, Fields L, Filkins A, Fine R, Gago AM, Gallagher H, Gilligan SM, Gran R, Granados E, Harris DA, Henry S, Jena D, Jena S, Kleykamp J, Klustová A, Kordosky M, Last D, Le T, Lozano A, Lu XG, Maher E, Manly S, Mann WA, Mauger C, McFarland KS, Messerly B, Miller J, Moreno O, Morfín JG, Naples D, Nelson JK, Nguyen C, Paolone V, Perdue GN, Plows KJ, Ramírez MA, Ransome RD, Ray H, Ruterbories D, Schellman H, Salinas CJS, Su H, Sultana M, Syrotenko VS, Valencia E, Vaughan NH, Waldron AV, Wascko MO, Wret C, Yaeggy B, Zazueta L.   +68 more
europepmc   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Gravitational Form Factors of the Deuteron

Acta Physica Polonica B
The gravitational form factors of the deuteron are calculated in the framework of non-relativistic chiral effective field theory. Non-relativistic reduction of the matrix element of the energy-momentum tensor operator for spin-one systems is worked out, and the gravitational form factors of the deuteron are extracted from the three-point function of ...
Panteleeva, J.Yu., Epelbaum, E., Gasparyan, A.M., Gegelia, J.   +3 more
openaire   +2 more sources

Factor Substitution and Unobserved Factor Quality in Nursing Homes [PDF]

This paper studies factor substitution in one important sector: the nursing home industry. Specifically, we measure the extent to which nursing homes substitute materials for labor when labor becomes relatively more expensive.
John Cawley, Richard A. Hirth, David C. Grabowski   +2 more
core  

The Involvement in Alcoholics Anonymous Scale - Short Form: Factor Structure & Validation. [PDF]

Subst Use Misuse, 2023
Beasley CR, LaBelle O, Vest N, Olson B, Skinner MD, Ferrari JR, Jason LA.   +6 more
europepmc   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Form factor

, 2019
We consider the lightcone sum-rule (LCSR) description of the pionphoton transition form factor in combination with the renormalization group of QCD.
S. V. Mikhailov, N. G. Stefanis, A. V. Pimikov, C. Ayala   +3 more
core   +1 more source