Results 111 to 120 of about 25,005,250 (309)

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Learning Concept Hierarchies from Text Corpora using Formal Concept Analysis [PDF]

, 2004
Cimiano P, Hotho A, Staab S. Learning Concept Hierarchies from Text Corpora using Formal Concept Analysis. Karlsruhe: Universität Karlsruhe, Institut für Angewandte Informatik und Formale Beschreibungsverfahren (AIFB ...
Staab, Steffen, Hotho, Andreas, Cimiano, Philipp ; https://orcid.org/   +2 more
core  

A formal actor-based model for streaming the future

, 2020
\u3cp\u3eAsynchronous Actor-based programming has gained increasing attention as a model of concurrency and distribution. The Abstract Behavioral Specification (ABS) language is an actor-based programming language that has been developed for both the ...
Azadbakht, Keyvan, Boer, Frank S de, Vink, EP Erik de, de Boer, Frank S., Bezirgiannis, Nikolaos, de Vink, Erik   +5 more
core   +1 more source

Research on certificateless anonymous authentication and key agreement scheme of vehicle network based on CPN

Tongxin xuebao
To address the shortcomings of existing authentication schemes in vehicle networks, which commonly suffer from key escrow issues, as well as the lack of consideration for lightweight deployment and secure rapid authentication of compute-constrained ...
ZHENG Lu, FENG Tao, SU Chunhua
doaj  

Formal Analysis of the Security Protocol with Timestamp Using SPIN. [PDF]

Comput Intell Neurosci, 2022
Xiao M, Song W, Yang K, OuYang R, Zhao H.   +4 more
europepmc   +1 more source

The BRST analysis of the Stückelberg formalism

, 1995
The Stuckelberg formalism can be regarded as a field-enlarging transformation that introduces an additional gauge symmetry to the considered model. We define and calculate the appropriate BRST charge. The physical state condition, demanding that a physical state is to be annihilated by the BRST charge, is shown to be equivalent to the Stuckelberg ...
Kogerles, R., Sładkowski, Jan
openaire   +4 more sources

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Terrorist threat assessment with formal concept analysis. [PDF]

The National Police Service Agency of the Netherlands developed a model to classify (potential) jihadists in four sequential phases of radicalism. The goal of the model is to signal the potential jihadist as early as possible to prevent him or her to ...
Morsing, Shanti, Elzinga, Paul, Dedene, Guido, Poelmans, Jonas, Viaene, Stijn   +4 more
core  

A formal analysis method for composition protocol based on model checking. [PDF]

Sci Rep, 2022
Xiao M, Zhao H, Yang K, Ouyang R, Song W.   +4 more
europepmc   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source