Results 81 to 90 of about 25,005,250 (309)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Interpreting the neural code with formal concept analysis [PDF]
This contribution is in volume 1 of 3 for this title.We propose a novel application of Formal Concept Analysis (FCA) to neural decoding: instead of just trying to figure out which stimulus was presented, we demonstrate how to explore the semantic ...
Endres, D, Foldiak, Peter
core +2 more sources
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
An Analysis of Spatial Construction in Pictorial Art from the Perspective of Formalism
“Space,” as a fundamental conceptual term, has been frequently and widely applied within various disciplines, such as sociology, architecture, philosophy, math, art, and so forth.
Hanping Feng, Safrizal Shahir
doaj +1 more source
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Formal modeling and security analysis method of security protocol based on CPN
To solve the problem of modeling and analyzing with colored Petri net (CPN), which was determining vulnerabilities in hole location but couldn’t identify any attack path, and the problem of when the introduction of the attacker model, the number of ...
Xiang GONG, Tao FENG, Jinze DU
doaj
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Towards a Formal Verification Methodology for Collective Robotic Systems [PDF]
We introduce a UML-based notation for graphically modeling systems’ security aspects in a simple and intuitive way and a model-driven process that transforms graphical specifications of access control policies in XACML.
Dorigo, Marco +23 more
core +1 more source
Qin J, Fan G, Lv Y, et al. Int J Nanomedicine. 2025;20:3861—3875. The authors have advised there is an error in Scheme 1 on page 3863. Specifically, a boron atom was incorrectly depicted as a nitrogen atom. The correct Scheme 1 is shown below.
Qin J +11 more
doaj

