Results 81 to 90 of about 25,005,250 (309)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Interpreting the neural code with formal concept analysis [PDF]

open access: yes, 2012
This contribution is in volume 1 of 3 for this title.We propose a novel application of Formal Concept Analysis (FCA) to neural decoding: instead of just trying to figure out which stimulus was presented, we demonstrate how to explore the semantic ...
Endres, D, Foldiak, Peter
core   +2 more sources

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

An Analysis of Spatial Construction in Pictorial Art from the Perspective of Formalism

open access: yesHarmonia: Journal of Arts Research and Education
“Space,” as a fundamental conceptual term, has been frequently and widely applied within various disciplines, such as sociology, architecture, philosophy, math, art, and so forth.
Hanping Feng, Safrizal Shahir
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Formal modeling and security analysis method of security protocol based on CPN

open access: yesTongxin xuebao, 2021
To solve the problem of modeling and analyzing with colored Petri net (CPN), which was determining vulnerabilities in hole location but couldn’t identify any attack path, and the problem of when the introduction of the attacker model, the number of ...
Xiang GONG, Tao FENG, Jinze DU
doaj  

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Towards a Formal Verification Methodology for Collective Robotic Systems [PDF]

open access: yes, 2012
We introduce a UML-based notation for graphically modeling systems’ security aspects in a simple and intuitive way and a model-driven process that transforms graphical specifications of access control policies in XACML.
Dorigo, Marco   +23 more
core   +1 more source

Dynamic Covalent Bond-Based Nanoassembly of Curcumin to Enhance the Selective Photothermal Therapy for Tumor Treatment [Corrigendum]

open access: yesInternational Journal of Nanomedicine
Qin J, Fan G, Lv Y, et al. Int J Nanomedicine. 2025;20:3861—3875. The authors have advised there is an error in Scheme 1 on page 3863. Specifically, a boron atom was incorrectly depicted as a nitrogen atom. The correct Scheme 1 is shown below.
Qin J   +11 more
doaj  

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