Results 81 to 90 of about 1,347,993 (267)

Design process of the Memorial Cathedral for World Peace (1954), Hiroshima, by Togo Murano (Part 3): Formal manipulations observed in the process of schematic design of the cathedral (1948)

open access: yesJapan Architectural Review
The collection of Kyoto Institute of Technology features numerous sketches and drawings scanning wide variety of exterior compositions of the cathedral.
Yoshito Tomioka, Chikako Tabata
doaj   +1 more source

A Specification-Based Semi-Formal Functional Verification Method by a Stage Transition Graph Model

open access: yesIEEE Access, 2019
The semi-formal verification method, in which the functionality is formally specified and the checking is undertaken through the formal model-based simulation, has been a promising choice for the functional verification of hardware designs.
Zhao Lv   +3 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

THE FORMAL METHOD IN LITERARY SCHOLARSHIP

open access: yesGragoatá, 2014
Reviewed book: MEDVIÉDEV, Pável Nikoláievitch. O método formal nos estudos literários: introdução crítica a uma poética sociológica. Trad. Sheila Camargo Grillo e Ekaterina Vólkova Américo. São Paulo: Contexto, 2012. 269p.
Anderson Cristiano da Silva   +1 more
doaj  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Formal modeling and analyzing method for database security policy

open access: yesTongxin xuebao, 2015
Because of the high-level abstraction,insufficient description of database states and constraints,it was difficult to find the tiny flaws in design and implementation.Based on PVS,a method for formal description and analysis of data-base security policy ...
Rong WANG   +3 more
doaj   +2 more sources

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