Results 91 to 100 of about 1,135,516 (291)
Decoding the Role of Epigenetics in Breast Cancer Using Formal Modeling and Machine-Learning Methods. [PDF]
Front Mol Biosci, 2022 Asim A, Kiani YS, Saeed MT, Jabeen I.
europepmc +1 more source
The Public Health Impact of Needle Exchange Programs in the United States and Abroad: Summary, Conclusions, and Recommendations [PDF]
, 1993 The goal of the project was: "To assess the public health impact of needle exchange programs." Fourteen research questions were identified; Chapters 5 through 18 of Volume I of the report each address one of these research questions.
Arthur L. Reingold, Peter Lurie
core
Formal Neighbourhoods and Formal Models of Non-Degenerate Arcs
Proceedings of the Bulgarian Academy of Sciences, 2022 An important result about the geometry of the arc space of an algebraic variety is the theorem of Drinfeld–Grinberg–Kazhdan, representing the formal neighbourhood of a non-degenerate arc. We start with a brief review of some important results and notions. Then the complete proof of the theorem with examples is given.
openaire +2 more sources
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Does the Principle of Compositionality Explain Productivity? For a Pluralist View of the Role of Formal Languages as Models [PDF]
, 2017 One of the main motivations for having a compositional semantics is the account of the productivity of natural languages. Formal languages are often part of the account of productivity, i.e., of how beings with finite capaci- ties are able to produce and
Perini-Santos, Ernesto
core
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Formal Analysis Of Use Case Diagrams
Computer Science, 2010 Use case diagrams play an important role in modeling with UML. Careful modeling is crucialin obtaining a correct and efficient system architecture. The paper refers to the formalanalysis of the use case diagrams.
Radosław Klimek, Piotr Szwed
doaj +1 more source
TGF-beta signaling proteins and the Protein Ontology [PDF]
, 2009 The Protein Ontology (PRO) is designed as a formal and principled Open Biomedical Ontologies (OBO) Foundry ontology for proteins. The components of PRO extend from a classification of proteins on the basis of evolutionary relationships at the ...
Cathy, Wu +7 more
core
The Foul Adversary: Formal Models [PDF]
, 2018 In classical notions of privacy in computer security, users attempt to keep their data private. A user that is bribed, extorted or blackmailed (i.e., coerced) may not do so. To get a general model of coercion, we strengthen the Dolev-Yao adversary with the ability to coerce others, to the foul adversary.
Dong, N, Muller, T
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