Results 61 to 70 of about 1,135,516 (291)
Integrating UML With Service Refinement for Requirements Modeling and Analysis
The Unified Modeling Language (UML) is the de facto standard for requirements modeling and analysis in the software industry. However, it lacks the ability of formal analysis and verification.
Yilong Yang +3 more
doaj +1 more source
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
A formal approach to spatio-temporal modeling of game systems
This article introduces FAST-GM (Formal Approach to Spatio-Temporal Game Modeling), a new unified approach to formal modeling of game entities and their interactions that integrates temporal and probabilistic dimensions, thus offering a comprehensive ...
V. V. Kugurakova
doaj +1 more source
Formal Modeling and Verification for MVB
Multifunction Vehicle Bus (MVB) is a critical component in the Train Communication Network (TCN), which is widely used in most of the modern train techniques of the transportation system.
Mo Xia +3 more
doaj +1 more source
Defining volunteer computing: a formal approach [PDF]
Volunteer computing resembles private desktop grids whereas desktop grids are not fully equivalent to volunteer computing. There are several attempts to distinguish and categorize them using informal and formal methods.
Attila Csaba Marosi, Robert Lovas
doaj +1 more source
Modelers of molecular signaling networks must cope with the combinatorial explosion of protein states generated by post-translational modifications and complex formations. Rule-based models provide a powerful alternative to approaches that require an explicit enumeration of all possible molecular species of a system [1,2]. Such models consist of formal
openaire +2 more sources
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Component-Based Formal Modeling of PLC Systems
Functional validation is an important task in complex embedded system. The formal modeling of PLC system for verification is a rough task. Good verification model should be faithful and concise.
Rui Wang +4 more
doaj +1 more source
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Modeling and verification of the correct behavior of embedded real-time systems with strict timing constraints is a well-known and important problem. Failing to fulfill a deadline in system operation can have severe consequences in the practical case ...
Libero Nigro, Franco Cicirelli
doaj +1 more source

