Results 131 to 140 of about 81,395 (299)
A literature-based approach to annotation and browsing of Web resources
The emerging Semantic Web technologies critically depend on the availability of shared knowledge representations called ontologies, which are intended to encode consensual knowledge about specific domains.
Miguel A. Sicilia +3 more
doaj
Genetic and pharmacological inhibition of SLC11A1 functioning as an H+/Fe2+ antiporter–mediated lysosomal iron accumulation in microglia promotes lysosomal lumen acidification, increases CTSD expression, enhances lysosomal myelin debris uptake and degradation, and promotes repair following white matter stroke. ABSTRACT White matter stroke (WMS) results
Lingling Qiu +11 more
wiley +1 more source
Logic for Husserl is a science of science, a science of what all sciences have in common in their modes of validation. Thus logic deals with universal laws relating to truth, to deduction, to verification and falsification, and with laws relating to theory as such, and to what makes for theoretical unity, both on the side of the propositions of a ...
openaire +2 more sources
Schematic illustration demonstrating that hepatic Mettl3 depletion significantly elevates the secretion of Mif and Csf1. This elevation facilitates Trem2+ macrophage infiltration and triggers cholangiocyte remodeling through the Spp1‐Cd44 interaction, resulting in spontaneous PSC development in vivo.
Wenting Pan +19 more
wiley +1 more source
Object Ontologies as a Priori Models for Logical-Probabilistic Machine Learning
Logical-probabilistic machine learning (LPML) is an AI method able to explicitly work with a priori knowledge represented in data models. This feature significantly complements traditional deep learning knowledge acquiring.
D. N. Gavrilin, A.V. Mantsivoda
doaj +1 more source
This study presents a 3D lymphoid tissue model engineered from adipose‐derived stem cells differentiated into fibroblastic reticular cell–like networks and co‐cultured with immune cells. The engineered system successfully generates antigen‐specific antibodies and cytokine responses, providing a platform for studying adaptive immunity, vaccine efficacy,
Mei ElGindi, Shaza Karaman, Jeremy Teo
wiley +1 more source
Upregulated TRMT6 forms aberrant hypermethylation of a specific tRNA pool and serves as a predictor of poor prognosis in TNBC. This m1A modification in tRNAs enhances translation of FTH1 and FTL, reducing the pool of bioavailable Fe2⁺. Reduced Fe2+ availability impairs RSL3‐induced lipid peroxidation and tumor progression.
Yuqing Lei +12 more
wiley +1 more source
Between Heaven and Earth: The Common Core of Basic Formal Ontology
This paper critically examines the relationship between Basic Formal Ontology (BFO) and the Common Core Ontologies (CCO), offering a comprehensive discussion of their theoretical foundations, design patterns, and implementation practices.
JOHN BEVERLEY
doaj
MGM as a Large‐Scale Pretrained Foundation Model for Microbiome Analyses in Diverse Contexts
We present the Microbial General Model (MGM), a transformer‐based foundation model pretrained on over 260,000 microbiome samples. MGM learns contextualized microbial representations via self‐supervised language modeling, enabling robust transfer learning, cross‐regional generalization, keystone taxa discovery, and prompt‐guided generation of realistic,
Haohong Zhang +5 more
wiley +1 more source
Effects of guideline-based training on the quality of formal ontologies: a randomized controlled trial. [PDF]
Boeker M +6 more
europepmc +1 more source

