Results 61 to 70 of about 81,395 (299)
This paper addresses issues associated with the development of eLearning software systems. The development of software systems in general is a highly complex process, and a number of methodologies and models have been developed to help address some of ...
Claire Gordon +2 more
doaj +1 more source
Spatial groundings for meaningful symbols [PDF]
The increasing availability of ontologies raises the need to establish relationships and make inferences across heterogeneous knowledge models. The approach proposed and supported by knowledge representation standards consists in establishing formal ...
Dietze, Stefan, Tanasescu, Vlad
core +2 more sources
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
A First-Order Logic Formalization of the Industrial Ontology Foundry Signature Using Basic Formal Ontology [PDF]
Basic Formal Ontology (BFO) is a top-level ontology used in hundreds of active projects in scientific and other domains. BFO has been selected to serve as top-level ontology in the Industrial Ontologies Foundry (IOF), an initiative to create a suite of ...
Ameri, Farhad +6 more
core
Measuring Expert Performance at Manually Classifying Domain Entities under Upper Ontology Classes
Classifying entities in domain ontologies under upper ontology classes is a recommended task in ontology engineering to facilitate semantic interoperability and modelling consistency.
Lord, Phillip +3 more
core +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
THE CIDOC CRM GAME: A Serious Game Approach to Ontology Learning [PDF]
Formal ontologies such as CIDOC CRM (Conceptual Reference Model) form part of the central strategy for the medium and longterm integration of cultural heritage data to allow for its greater valorization and dissemination.
A. Guillem, G. Bruseker
doaj +1 more source
An ontology for carcinoma classification for clinical bioinformatics [PDF]
There are a number of existing classifications and staging schemes for carcinomas, one of the most frequently used being the TNM classification.
Kumar, Anand +4 more
core
Artefacts in Formal Ontology [PDF]
This chapter illustrates ontological systems, hereafter referred to as ontologies, which satisfy the two main requirements of being formal and foundational. Ontology is formal if it is expressed in a logic language endowed with clear semantics (for instance, in model-theoretic terms as first-order predicate logic).
Borgo Stefano, Vieu Laure
openaire +2 more sources
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li +6 more
wiley +1 more source

