Results 131 to 140 of about 18,881 (225)

Leonurine Ameliorates Doxorubicin‐Induced Cardiotoxicity via STING/NF‐κB/NLRP3 Inflammasome Signaling Pathway

Advanced Science, EarlyView.
ABSTRACT Doxorubicin‐induced cardiomyopathy (DIC) remains a dose‐limiting clinical challenge. This study reveals that cardiac vascular endothelial cells (CVECs) act as initial sensors of doxorubicin cardiotoxicity: circulating doxorubicin activates the cGAS‑STING pathway in CVECs, triggering NLRP3 inflammasome‑mediated pyroptosis and release of ...
Wang Jun, Chen Xiaoyang, Xu Jianglin, Yang Zhi, Tao Meijiao, He Jiale, Zhao Jiangfeng, Hei Xuanding, Xu Xuegong, Wang Wei, Li Chun   +10 more
wiley   +1 more source

Infinite groups acting on formal power series rings

Journal of Algebra, 1978
Brewer, J., Jooste, T., le Riche, L., Sheridan, M., Martens, E., van Rooyen, W., Müller, A.   +6 more
openaire   +2 more sources

De Novo Design of Membrane‐Targeting Antimicrobial Peptides Against Gram‐Negative Bacteria Using a Generative Artificial Intelligence Framework

Advanced Science, EarlyView.
Antimicrobial resistance caused by Gram‐negative bacteria remains difficult to overcome due to the protective outer membrane. To address this challenge, a multi‐condition constrained generative AI framework, GenMTAMP is proposed for de novo membrane‐targeting antimicrobial peptide design by integrating physicochemical and spatial structure descriptors.
Jingxiao Yu, Da‐Wen Sun, QingYi Wei, Yibing Zhang, Jidong Tang, Hongbin Pu   +5 more
wiley   +1 more source

A Systematic Topological Picture of ROS Scavenging Activity via Formal Hydrogen Atom Transfer in Phenols and Polyphenols. [PDF]

J Org Chem
Zeppilli D, Filippi M, Madabeni A, Orian L.   +3 more
europepmc   +1 more source

Stress Accumulation Induced by Ion Exchange for Synchronous Modulation of Mode and Wavelength in Microlasers

Advanced Science, EarlyView.
This work demonstrates a paradigm‐shifting strategy to simultaneously achieve broadband wavelength tunability and single‐mode control within a single perovskite microwire structure. Using a facile heating‐assisted solid–solid anion‐exchange strategy, we synthesized phase‐pure CsPbClxBr3‐x microwires that exhibit the widest reported continuous lasing ...
Bingwang Yang, Lingling Sun, Jinhui Wang, Jitao Li, Peng Wan, Daning Shi, Caixia Kan, Mingming Jiang   +7 more
wiley   +1 more source

Unusual Thermally Induced Blueshift and Emission Amplification of Mn2+ Ions Enable Filter‐Free Luminescent Thermal Imaging

Advanced Science, EarlyView.
ABSTRACT The shift from point‐based thermal sensing to filter‐free thermal imaging requires luminescent thermometers that exhibit pronounced and thermally driven spectral changes within spectral regions matching the sensitivity profiles of the red, green and blue (RGB) channels of a digital camera.
Y. Abe, M. Szymczak, J. Zeler, L. Marciniak   +3 more
wiley   +1 more source

Accurately Deciphering Tissue Heterogeneity From Spatial Multi‐Modal and Multi‐Omics With STransformer

Advanced Science, EarlyView.
STransformer is a unified deep learning framework designed to seamlessly accommodate a comprehensive landscape of spatial data. By simultaneously capturing short‐range cellular interactions and tissue‐wide semantic patterns, it extracts robust representations to accurately dissect complex tissue heterogeneity.
Xingyi Li, Jialuo Xu, Gaoyuan Du, Xiangting Jia, Dongmin Zhao, Chunyan Zhou, Kexin Xiao, Jia Gu, Junnan Zhu, Xuequn Shang   +9 more
wiley   +1 more source

Clinical Outcomes and Complications After INTACS Implantation in Keratoconus: A Systematic Review. [PDF]

J Clin Med
Czuj-Porębska W, Wylęgała A, Martyka A, Gospodarczyk N, Piłat J, Wylęgała E, Wowra B.   +6 more
europepmc   +1 more source

3D‐Printed Magnetoelectronics for Interactive Appliances and Self‐Aware 4D‐Printed Mechatronics

Advanced Science, EarlyView.
3D‐printed magnetoelectronics integrate high‐performance magnetic field sensing directly into complex structural components. Flexible spring and cross‐shaped sensors exhibit giant magnetoimpedance and 3D Hall sensing for vector field reconstruction. Applications include smart‐home switches, robotic joysticks, volumetric magnetometers, and self‐aware 4D‐
Eduardo Sergio Oliveros‐Mata, Anna Martin Vilardell, Fabian Ganss, Christoph Leyens, Lukas Stepien, Denys Makarov   +5 more
wiley   +1 more source

Design and construction of a pyrolysis unit - demonstrated in connection with gas chromatography-ion mobility spectrometry. [PDF]

HardwareX
Lippmann M, Hitzemann M, Eckhardt A, Röckrath D, Zimmermann S.   +4 more
europepmc   +1 more source