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Advanced Science, EarlyView.A real‐world model of structured animal product restriction practiced for religious reasons reveals the dynamic adaptability of the human gut microbiome to dietary change and uncovers reductions in diversity and rare taxa loss. Integrated microbiome, metabolomic, and proteomic analyses uncover coordinated taxonomic and molecular shifts and identify ...
Christina Emmanouil +7 more
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Advanced Science, EarlyView.Hybrid FRET–BRET biosensors were developed to monitor RAF–KRAS interactions in living cells. These sensors enable real‐time visualization of interaction dynamics, quantitative spectral analysis, and validation of mutation‐selective inhibitors, providing a versatile platform for probing KRAS regulation and therapeutic responses. ABSTRACT The RAS–RAF–MEK–
Jeong‐Min Go +12 more
wiley +1 more source
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Formal Requirements Specification
Proceedings of the 2020 9th International Conference on Software and Information Engineering (ICSIE), 2020Model Driven Software Engineering (MDSE) has become a widely adopted approach in software development industry. Besides other software development phases, specifying requirements formally, is a crucial activity for developing model based software systems.
Misbah Mehboob Awan +3 more
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Proceedings of the Conference on The Future of Software Engineering, 2000
Formal specifications have been a focus of software engineering research for many years and have been applied in a wide variety of settings. Their industrial use is still limited but has been steadily growing. After recalling the essence,role, usage, and pitfalls of formal specification, the paper reviews the main specification paradigms to date and ...
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Formal specifications have been a focus of software engineering research for many years and have been applied in a wide variety of settings. Their industrial use is still limited but has been steadily growing. After recalling the essence,role, usage, and pitfalls of formal specification, the paper reviews the main specification paradigms to date and ...
openaire +2 more sources
Evolving specifications formally
2011 IEEE 19th International Requirements Engineering Conference, 2011This paper presents a formal specification and analysis method motivated by issues faced during early stages of requirements development for automotive features. At this early stage of development, only overall goals of features are understood, and there is a need to discover all possible scenarios of operation.
Prahladavaradan Sampath +2 more
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Executing formal specifications
Proceedings of the symposium on Testing, analysis, and verification, 1991ASTRAL is a formal specification language for realtime systems. This paper discusses how ASTRAL’s semantics are specified in terms of TRIO, a formal realtime logic language. This allows ASTRAL specifications to be formally analyzed by translating them into TRIO and then using the existing validation theory for TRIO specifications.
Carlo Ghezzi, Richard A. Kennerer
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2005
Formal Description Techniques (FDTs) that should be capable to express the OSI Protocols and Services are confronted with unprecedented requirements in terms of the abstraction level at which the OSI architectural concepts need to be expressed as well as the high complexity of the OSI standards.
VISSERS C. A, SCOLLO, Giuseppe
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Formal Description Techniques (FDTs) that should be capable to express the OSI Protocols and Services are confronted with unprecedented requirements in terms of the abstraction level at which the OSI architectural concepts need to be expressed as well as the high complexity of the OSI standards.
VISSERS C. A, SCOLLO, Giuseppe
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Formal Dialectic Specification
2005Formal dialectic systems have been suggested as a means to model inter-agent communication in multi-agent systems. The formal dialectic systems of Hamblin are practical models for the computational implementation of such a system of argumentative dialogue.
Wells, Simon, Reed, Chris
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Integrating semi-formal and formal software specification techniques
Information Systems, 1998In this paper, we report on the integration of informal, semiformal and formal system specification techniques. We present a framework for system specification called TRADE, within which several well-known semiformal specification techniques are placed.
Wieringa, Roelf J., Dubois, Eric
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Formal specification languages
Electronics and Power, 1986Bugs in computer software are still commonplace. The problem is often due to inadequate specification of the requirements. Formal specification is proposed as a solution, but is it practical?
John Parker, Graham Titterington
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