Results 71 to 80 of about 2,084,052 (380)
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková +14 more
wiley +1 more source
Concurrency specification using Event-based Specification Chart [PDF]
Architecting framework proposed in [1] can be used efficiently for developing concurrency-intensive systems only if there exist languages and tools corresponding to the described concepts.
Dumitru Ciorba, Victor Besliu
doaj
Formal Specification and Verification of Self-Adaptive Concurrent Systems
The assurance of required quality properties is one of the major challenges in self-adaptive systems (SASs). SASs have the capability to adapt their dynamic behavior autonomously at runtime due to uncertain changes in the environment.
Muhammad Ilyas Fakhir +1 more
doaj +1 more source
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser +14 more
wiley +1 more source
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
Formal Synthesis of Stochastic Systems via Control Barrier Certificates [PDF]
This article focuses on synthesizing control policies for discrete-time stochastic control systems together with a lower bound on the probability that the systems satisfy the complex temporal properties. The desired properties of the system are expressed
Pushpak Jagtap +2 more
semanticscholar +1 more source
In over 50% of non‐metastatic breast cancer patients, circulating tumor cells (CTCs) along the whole epithelial‐mesenchymal transition spectrum are detected. Total CTC number and individual phenotypes relate to aggressive disease characteristics, including lymph node involvement and higher tumor proliferation. At the single‐cell level, mesenchymal CTCs
Justyna Topa +14 more
wiley +1 more source
HSP70 governs permeability and mechanotransduction in primary human endothelial cells
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez +5 more
wiley +1 more source
Method specification for automated evaluation of documents formal quality
Automated documents processing allows production of large amount of documents. Formal quality of the documents is very important as it contributes to better understanding and information transmission.
Petra Talandová, Jiří Rybička
doaj +1 more source
AR2B: FORMALIZATION OF ARABIC TEXTS WITH EVENT-B
Transforming natural software requirements into a more formal specification is difficult and may be an excellent application for natural language processing. This problem is not recent.
Kheira-Zineb Bousmaha Ossoukine +1 more
doaj +1 more source

