Results 111 to 120 of about 1,803,900 (290)

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

The integration of software specification, verification, and testing techniques with software requirements and design processes. [PDF]

open access: yes, 1995
Specifying, verifying, and testing software requirements and design are very important tasks in the software development process and must be taken seriously.
Chantatub, Wachara
core   +2 more sources

Deductive Functional Verification of Safety-Critical Embedded C-Code: An Experience Report

open access: yes, 2017
This paper summarizes our experiences from an exercise in deductive verification of functional properties of automotive embedded Ccode in an industrial setting.
Lidström, Christian,   +7 more
core   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

open access: yesFEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão   +3 more
wiley   +1 more source

Proceedings of Formal Methods in Computer Aided Design, FMCAD 2018 [PDF]

open access: yes, 2018
October 30 – November 2, 2018 in Austin, Texas, USATable of Contents: INVITED PAPERS -- Formal Verification of Deep Neural Networks / by Nina Narodytska (p. 1) -- Formal Verification of Unsatisfiability Results / by Marijn Heule (p.
Formal Methods in Computer Aided Design
core  

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Streamlining Temporal Formal Verification over Columnar Databases

open access: yesInformation
Recent findings demonstrate how database technology enhances the computation of formal verification tasks expressible in linear time logic for finite traces (LTLf).
Giacomo Bergami
doaj   +1 more source

Formal verification of Matrix based MATLAB models using interactive theorem proving. [PDF]

open access: yesPeerJ Comput Sci, 2021
Gauhar A   +4 more
europepmc   +1 more source

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