Results 121 to 130 of about 449,052 (266)

Seven years in formalin: the burden of metabarcoding mesozooplankton preserved in buffered formalin from the northern Adriatic Sea. [PDF]

J Plankton Res
Chiarabelli E, de Olazabal A, Goruppi A, D'Ambros Burchio S, Sollitto M, Tirelli V, Pallavicini A.   +6 more
europepmc   +1 more source

Formalin burn [PDF]

British Dental Journal, 2010
A. C. P. Ribeiro, L. E. Simonato, A. R. Santos-Silva, N. Perri de Moraes, A. M. P. Soubhia   +4 more
openaire   +1 more source

A C‐Nucleoside Analogue of Cordycepin With High Metabolic Stability and Potent Anti‐Psoriatic Activity via Microneedle Delivery

Advanced Science, EarlyView.
This work identified CPD3a as a potent, stable C‐nucleoside cordycepin derivative. When formulated into microneedle array for topical treatment, it ameliorated psoriasis by rebalancing immunity and enhancing antioxidant defenses. ABSTRACT Psoriasis is a chronic inflammatory disorder characterized by immune dysregulation and epidermal hyperplasia ...
Wenfang Pan, Xinyue Shao, Yuanchen Zhong, Xujie Sun, Lixuan Yin, Zongyan He, Tianqun Lang, Yuanchao Xie   +7 more
wiley   +1 more source

Good DNA- and sufficient RNA integrity in formalin-free paraffin-embedded tissues. [PDF]

PLoS One
Niemantsverdriet M, Methorst N, Hoek SY, Knol A, Hoogland AM.   +4 more
europepmc   +1 more source

Chimeric IL‐6/4R‐LL37 Engineered Macrophages Achieve Synchronized Inflammation Control and Antimicrobial Defence in Sepsis

Advanced Science, EarlyView.
Engineered macrophages programmed in situ by LNP‐delivered IL‐6/4 fusion and LL37 mRNAs simultaneously dampen cytokine storm, promote M2‐like repair, and enhance direct bacterial killing in sepsis. This combinatorial strategy restores T cell and macrophage function, lowers organ bacterial burden, and improves survival, highlighting a precision, host ...
Tianyang Jie, Zheyu Zhang, Hao Zhang, Linke Bian, Penglong Zheng, Sijia Zhou, Minqi Wang, Mingyu Qu, Yufei Wang, Xinhua Qu, Bing Yue   +10 more
wiley   +1 more source

The role of <i>Lactobacillus plantarum</i> (camel milk isolate) in inflammation and acute pain modulation: a comparative study with acetaminophen in animal model. [PDF]

Ann Med Surg (Lond)
Ahmadi S, Khosravipour N, Pedram-Jafari S, Dashti S, Taherkhani S, Nasiraie LR, Janzadeh A.   +6 more
europepmc   +1 more source

Repurposing a Small Molecule Plant Hormone as a Tunable ON‐Switch for CAR‐T Cell Immunotherapy

Advanced Science, EarlyView.
By engineering a receptor system integrating the plant auxin receptor AFB1 with its co‐receptor IAA7, we enable ligand‐dependent interactions triggered by the plant hormone auxins. This design allows rapid, reversible, and dose‐dependent T cell activation, resulting in potent cytotoxicity against B‐cell lymphoma in vitro and in vivo.
Hongxiang Zeng, Lei Zheng, Rongkun Tao, Sirui Zheng, Yanke Zhong, Yongxia Niu, Peng Zhang, Xiang Ma, Chen Yang, Min Zhang, Fuyu Duan, Jing Yang, Xuan Wei, Xiang Zhou, Zhenbiao Yang, Zhaoxi Sun, Qizhou Lian   +16 more
wiley   +1 more source

Deep Learning-Based Quantification of Spontaneous Pain Behaviours in Mice. [PDF]

Eur J Pain
Zanoletti M, Bellantoni E, Pombo Gomes L, Quadros Dos Santos ML, Souza Monteiro de Araújo D, De Siena G, Qader Kudsi S, Nassini R, Laurino M, De Logu F.   +9 more
europepmc   +1 more source

circZNF148 Drives Glucose Metabolism Reprogramming to Enhance Metastasis and Immune Evasion via HK1 Stabilization in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
CircZNF148 stabilizes HK1 through deubiquitinase recruitment, thereby enhancing glycolysis and lactate production. Elevated lactate promotes PD‑L1 lactylation and membrane accumulation while suppressing CD8+ T‐cell cytotoxicity, collectively facilitating immune evasion and malignant progression in TNBC.
Yuhan Jin, Wenjing Zhao, Lei Wang, Jianing Wang, Keying Zhao, Dan Luo, Yifei Wang, Yuxia Yang, Jingze Yang, Yaming Li, Tong Chen, Dianwen Han, Zekun Wang, Xiaoyan Li, Bing Chen, Lijuan Wang, Yiran Liang, Qifeng Yang   +17 more
wiley   +1 more source

Leveraging the unique properties of RNA aptamers to quantify the fraction of receptors occupied by ligands. [PDF]

Mol Ther Nucleic Acids
Weiner GJ.
europepmc   +1 more source