Results 201 to 210 of about 15,779,296 (295)

Impact of estrous cycle, gonadectomy (ovariectomy or castration), and selective G-protein estrogen receptor agonism on inflammatory pain in wild-type mice. [PDF]

Mol Pain
Barnes RC, Alanis A, Quick H, Guindon J.
europepmc   +1 more source

High‐Content SRS Imaging Unveils Altered Cholesterol Metabolism in Ovarian Cancers Under CAR‐T Treatment

Advanced Science, EarlyView.
High‐content Stimulated Raman Scattering (SRS) Imaging reveals that ovarian cancer cells surviving Chimeric Antigen Receptor (CAR) ‐T cell challenge exhibit increased cholesterol esterification. Pharmacological inhibition of this pathway with Avasimibe significantly enhances CAR‐T induced killing of ovarian cancer cells by reducing cancer cell ...
Chinmayee V. Prabhu Dessai, Zhuoying Huang, Haonan Lin, Guangrui Ding, Hongjian He, Menna Siddiqui, Meng Zhang, Wilson Wong, Ji‐Xin Cheng   +8 more
wiley   +1 more source

Building ultrasound-guided procedure skills in regional anesthesiology: simulation training with a formalin-embalmed cadaver model. [PDF]

BMC Anesthesiol
Mason NL, Cohen E, Ganga K, Zapata I, Hawke A, Peck M.   +5 more
europepmc   +1 more source

Protein biomarker discovery in neural tissue: a comparative analysis of immunoassay and colloidal gold lateral flow assay method. [PDF]

Front Neurol
Su Z, Huang K, Wang Z.
europepmc   +1 more source

Trans-Chalcone alleviates overt pain-like behavior by targeting the activation of nociceptive neuron TRPV1 and TRPA1 channels. [PDF]

Inflammopharmacology
Piva M, Yaekashi KM, Pereira TGO, Bertozzi MM, Pinho-Ribeiro FA, Calixto-Campos C, Camilios-Neto D, Borghi SM, Zarpelon-Schutz AC, Fattori V, Casagrande R, Verri WA.   +11 more
europepmc   +1 more source

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The interphase of the formalin test

Pain, 2014
The formalin test still surprises with its biphasic pain-related behavior resulting from a quiescent interphase that does not occur with other algogenic compounds and remains unexplained. The first phase has been attributed to TRPA1-mediated excitation of nociceptors, the second phase to their inflammatory and/or spinal sensitization.
M. Fischer, G. Carli, P. Raboisson, P. Reeh   +3 more
semanticscholar   +3 more sources

The formalin test: an evaluation of the method

Pain, 1992
The formalin test for nociception, which is predominantly used with rats and mice, involves moderate, continuous pain generated by injured tissue. In this way it differs from most traditional tests of nociception which rely upon brief stimuli of threshold intensity.
A. Tjølsen, O. Berge, S. Hunskaar, J. Rosland, K. Hole   +4 more
semanticscholar   +3 more sources

Modified formalin test: characteristic biphasic pain response

Pain, 1989
A modified formalin test in mice was investigated. The pain response curve induced by 0.5% formalin was biphasic, having 2 peaks, from 0 to 5 min (first phase) and from 15 to 20 min (second phase). A low concentration of formalin was used, allowing the effects of weak analgesics to be detected.
M. Shibata, T. Ohkubo, Hiroshi Takahashi, R. Inoki   +3 more
semanticscholar   +3 more sources

The formalin test in mice: effect of formalin concentration

Pain, 1990
The effect of different formalin concentrations on the nociceptive response in the formalin test was examined in mice. Subcutaneous formalin injection induces 2 distinct periods of high licking activity: an early phase lasting the first 5 min, and a late phase lasting 20-30 min after the injection.
J. Rosland, A. Tjølsen, Bjørn Mæhle, K. Hole   +3 more
semanticscholar   +3 more sources