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Carbon neutral hydrogen storage and release cycles based on dual-functional roles of formamides [PDF]

open access: yesNature Communications, 2023
The development of alternative clean energy carriers is a key challenge for our society. Carbon-based hydrogen storage materials are well-suited to undergo reversible (de)hydrogenation reactions and the development of catalysts for the individual process
Duo Wei   +4 more
doaj   +2 more sources

Modular assembly of chiral amino acid derivatives and peptides from commonly available feedstocks [PDF]

open access: yesNature Communications
α-Amino acids are fundamental components of proteins and natural molecules, with non-natural variants highly valued in both academia and industry for their ability to tune chemical, physical, and pharmaceutical properties.
Wei-Wei Ding   +4 more
doaj   +2 more sources

Synthesis, Structure and Cytoprotective Activity of New Derivatives of 4-Aryl-3-Aminopyridin-2(1H)-One [PDF]

open access: yesMolecules
As a continuation of our research on the synthesis and study of biological properties of new derivatives of 3-aminopyridin-2(1H)-ones, we investigated the Leuckart–Wallach and Eschweiler–Clarke reactions with selected 3-aminopyridin-2(1H)-ones and 3 ...
Zarina Shulgau   +8 more
doaj   +2 more sources

Deuterated reagents in multicomponent reactions to afford deuterium-labeled products [PDF]

open access: yesBeilstein Journal of Organic Chemistry
The utility of bio-isosteres is broad in drug discovery and methodology herein enables the preparation of deuterium-labeled products is the most fundamental of known bio-isosteric replacements.
Kevin Schofield   +7 more
doaj   +2 more sources

A More Sustainable Isocyanide Synthesis from N-Substituted Formamides Using Phosphorus Oxychloride in the Presence of Triethylamine as Solvent

open access: yesMolecules, 2022
A simple, green, and highly efficient protocol for the synthesis of isocyanides is described. The reaction involves dehydration of formamides with phosphorus oxychloride in the presence of triethylamine as solvent at 0 °C.
Sodeeq Aderotimi Salami   +2 more
doaj   +1 more source

N-Formylsaccharin: A Sweet(able) Formylating Agent in Mechanochemistry

open access: yesMolecules, 2022
The acylation of amines has always attracted a deep interest as a synthetic route due to its high versatility in organic chemistry and biochemical processes. The purpose of this article is to present a mechanochemical acylation procedure based on the use
Federico Cuccu   +3 more
doaj   +1 more source

Rapid one-pot radiosynthesis of [carbonyl-11C]formamides from primary amines and [11C]CO2

open access: yesEJNMMI Radiopharmacy and Chemistry, 2020
Background Formamides are common motifs of biologically-active compounds (e.g. formylated peptides) and are frequently employed as intermediates to yield a number of other functional groups.
Federico Luzi   +2 more
doaj   +1 more source

Silver Catalyzed Decarbonylative [3 + 2] Cycloaddition of Cyclobutenediones and Formamides

open access: yesMolecules, 2021
As an important moiety in natural products, N,O-acetal has attracted wide attention in the past few years. An efficient method to construct N,O-acetal has been developed.
Pengcheng Wang   +6 more
doaj   +1 more source

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